Apremilast

Name: Apremilast
Brand: Vaqora Chemicals
SKU: VQ-007319

About Apremilast

Vaqora Chemicals supplies Apremilast, a high-purity reference standard of Apremilast registered under CAS number 608141-41-9. With the molecular formula C22H24N2O7S, it has a molar mass of 460.5 g/mol. The IUPAC name is N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide. It is also known as Otezla or Apremilast (CC-10004).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Apremilast standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Apremilast in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	Apremilast
Catalogue No.	VQ-007319
CAS Number	608141-41-9
IUPAC name	N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
Molecular formula	C₂₂H₂₄N₂O₇S
Molecular weight	460.5 g/mol
Exact mass	460.1304
Grade	Reference Standard
HSN code	38229090
InChIKey	IMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILES	CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
PubChem CID	11561674

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 7
TPSA	127 Å²
Synonyms	Otezla, Apremilast (CC-10004), (S)-Apremilast, Apremilast- Bio-X, Otezla (TN), Apremilast (Standard), Apremilast (JAN/USAN), Apremilast Reference Standard, Apremilast - Bio-X trade mark, EX-A336, A9L

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P319, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apremilast?

The CAS Registry Number of Apremilast is 608141-41-9. It is also known as Otezla, Apremilast (CC-10004), (S)-Apremilast.

What is the molecular formula and molecular weight of Apremilast?

Apremilast has the molecular formula C22H24N2O7S and a molecular weight of 460.5 g/mol. Its IUPAC name is N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide.

What is Apremilast used for?

Apremilast is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apremilast can I order?

We supply Apremilast in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apremilast?

Yes. Every lot of Apremilast is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apremilast be shipped internationally?

Yes. Apremilast is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.