Cloxacillin

Name: Cloxacillin
Brand: Vaqora Chemicals
SKU: VQ-043123

About Cloxacillin

Cloxacillin (CAS 61-72-3) is an impurity of Oxacillin offered by Vaqora Chemicals. With the molecular formula C19H18ClN3O5S, it has a molar mass of 435.9 g/mol. Alternative names: Cloxacilline and Methocillin S.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Oxacillin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cloxacillin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Oxacillin

View every impurity, metabolite and intermediate we list for Oxacillin.

Oxacillin impurities

Specifications & identifiers

Chemical identifiers
Product name	Cloxacillin
Catalogue No.	VQ-043123
CAS Number	61-72-3
IUPAC name	(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular formula	C₁₉H₁₈ClN₃O₅S
Molecular weight	435.9 g/mol
Exact mass	435.0656
Grade	Reference Standard
HSN code	38229090
InChIKey	LQOLIRLGBULYKD-JKIFEVAISA-N
SMILES	CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O
PubChem CID	6098

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 7
TPSA	138 Å²
Synonyms	Cloxacilline, Methocillin S, Chloroxacillin, (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin, 6-(3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid, Cloxacillin, Sodium, Sodium, Cloxacillin, cloxacillinum natricum, Clossacillina [DCIT], BRL 1621, Methylchlorphenylisoxazoryl-penicillin, Tegopen (sodium monohydrate)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P260, P261, P264, P264 + P265, P271, P272, P280, P284, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P333 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cloxacillin?

The CAS Registry Number of Cloxacillin is 61-72-3. It is also known as Cloxacilline, Methocillin S, Chloroxacillin.

What is the molecular formula and molecular weight of Cloxacillin?

Cloxacillin has the molecular formula C19H18ClN3O5S and a molecular weight of 435.9 g/mol. Its IUPAC name is (2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

What is Cloxacillin used for?

Cloxacillin is supplied as a characterised reference material related to Oxacillin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cloxacillin can I order?

We supply Cloxacillin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cloxacillin?

Yes. Every lot of Cloxacillin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cloxacillin be shipped internationally?

Yes. Cloxacillin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.