Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl… 61260-15-9

Name: Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Brand: Vaqora Chemicals
SKU: VQ-013375

About Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate

Listed under CAS 61260-15-9, Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is a process intermediate or related compound of Olaparib available from Vaqora Chemicals. With the molecular formula C10H11O5P, it has a molar mass of 242.16 g/mol. The IUPAC name is 3-dimethoxyphosphoryl-3H-2-benzofuran-1-one. Common synonyms include 3-dimethoxyphosphoryl-3H-isobenzofuran-1-one and Olapali Intermediate 1.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Olaparib, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Olaparib

View every impurity, metabolite and intermediate we list for Olaparib.

Olaparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Catalogue No.	VQ-013375
CAS Number	61260-15-9
IUPAC name	3-dimethoxyphosphoryl-3H-2-benzofuran-1-one
Molecular formula	C₁₀H₁₁O₅P
Molecular weight	242.16 g/mol
Exact mass	242.0344
Grade	Reference Standard
InChIKey	KEKUNQAVGWOYDW-UHFFFAOYSA-N
SMILES	COP(=O)(C1C2=CC=CC=C2C(=O)O1)OC
PubChem CID	11118213

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	0 / 5
TPSA	61.8 Å²
Synonyms	(3-Oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid dimethyl ester, Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate, dimethyl (3-oxo-1,3-dihydro-2-benzofuran-1-yl)phosphonate, dimethyl 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonate, 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid, 3-dimethoxyphosphoryl-3H-isobenzofuran-1-one, Olapali Intermediate 1, dimethyl (3-oxo-1,3-di, Dimethyl(3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate, CS-M0104, Phthalide, 3-phosphono-, dimethyl ester, dimethyl 3-oxobenzo[c]furan-1-ylphosphonate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate?

The CAS Registry Number of Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is 61260-15-9. It is also known as (3-Oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid dimethyl ester, Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate, dimethyl (3-oxo-1,3-dihydro-2-benzofuran-1-yl)phosphonate.

What is the molecular formula and molecular weight of Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate?

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate has the molecular formula C10H11O5P and a molecular weight of 242.16 g/mol. Its IUPAC name is 3-dimethoxyphosphoryl-3H-2-benzofuran-1-one.

What is Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate used for?

Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is supplied as a characterised reference material related to Olaparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate can I order?

We supply Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate?

Yes. Every lot of Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate be shipped internationally?

Yes. Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.