Isoquinoline-8-carboxylic acid

About Isoquinoline-8-carboxylic acid

Isoquinoline-8-carboxylic acid is an impurity of Isoquinoline carrying the CAS registry number 61563-43-7. Formula C10H7NO2, molecular weight 173.17 g/mol. It is also known as 8-isoquinolinecarboxylic acid or Isoquinoline-8-carboxylic acid, AldrichCPR.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Isoquinoline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Isoquinoline-8-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isoquinoline

View every impurity, metabolite and intermediate we list for Isoquinoline.

Isoquinoline impurities

Specifications & identifiers

Chemical identifiers
Product name	Isoquinoline-8-carboxylic acid
Catalogue No.	VQ-050346
CAS Number	61563-43-7
IUPAC name	isoquinoline-8-carboxylic acid
Molecular formula	C₁₀H₇NO₂
Molecular weight	173.17 g/mol
Exact mass	173.0477
Grade	Reference Standard
HSN code	38229090
InChIKey	VMNZQPRIUSJCOH-UHFFFAOYSA-N
SMILES	C1=CC2=C(C=NC=C2)C(=C1)C(=O)O
PubChem CID	21393830

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 3
TPSA	50.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isoquinoline-8-carboxylic acid?

The CAS Registry Number of Isoquinoline-8-carboxylic acid is 61563-43-7. It is also known as 8-isoquinolinecarboxylic acid, Isoquinoline-8-carboxylic acid, AldrichCPR.

What is the molecular formula and molecular weight of Isoquinoline-8-carboxylic acid?

Isoquinoline-8-carboxylic acid has the molecular formula C10H7NO2 and a molecular weight of 173.17 g/mol. Its IUPAC name is isoquinoline-8-carboxylic acid.

What is Isoquinoline-8-carboxylic acid used for?

Isoquinoline-8-carboxylic acid is supplied as a characterised reference material related to Isoquinoline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isoquinoline-8-carboxylic acid can I order?

We supply Isoquinoline-8-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isoquinoline-8-carboxylic acid?

Yes. Every lot of Isoquinoline-8-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isoquinoline-8-carboxylic acid be shipped internationally?

Yes. Isoquinoline-8-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.