Propargyl Tosylate

About Propargyl Tosylate

Propargyl Tosylate is an impurity of Rasagiline carrying the CAS registry number 6165-76-0. With the molecular formula C10H10O3S, it has a molar mass of 210.25 g/mol. Its systematic (IUPAC) name is prop-2-ynyl 4-methylbenzenesulfonate. Common synonyms include Propargyl p-toluenesulfonate and p-TOLUENESULFONIC ACID, 2-PROPYNYL ESTER.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Rasagiline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rasagiline

View every impurity, metabolite and intermediate we list for Rasagiline.

Rasagiline impurities

Specifications & identifiers

Chemical identifiers
Product name	Propargyl Tosylate
Catalogue No.	VQ-044712
CAS Number	6165-76-0
IUPAC name	prop-2-ynyl 4-methylbenzenesulfonate
Molecular formula	C₁₀H₁₀O₃S
Molecular weight	210.25 g/mol
Exact mass	210.0351
Grade	Reference Standard
HSN code	38229090
InChIKey	LMBVCSFXFFROTA-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)OCC#C
PubChem CID	22547

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 3
TPSA	51.8 Å²
Synonyms	Propargyl p-toluenesulfonate, p-TOLUENESULFONIC ACID, 2-PROPYNYL ESTER, 2-Propyn-1-ol, 4-methylbenzenesulfonate, 2-propynyl p-toluenesulfonate, Prop-2-yn-1-yl 4-methylbenzenesulfonate, Propargyl p-toluene sulfonate, prop-2-yn-1-yl 4-methylbenzene-1-sulfonate, p-Toluenesulfonic Acid Propargyl Ester, Propargylp-toluenesulfonate, Propargyl p-toluenesulphonate, 2-Propynyl 4-methylbenzenesulfonate #

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Propargyl Tosylate?

The CAS Registry Number of Propargyl Tosylate is 6165-76-0. It is also known as Propargyl p-toluenesulfonate, p-TOLUENESULFONIC ACID, 2-PROPYNYL ESTER, 2-Propyn-1-ol, 4-methylbenzenesulfonate.

What is the molecular formula and molecular weight of Propargyl Tosylate?

Propargyl Tosylate has the molecular formula C10H10O3S and a molecular weight of 210.25 g/mol. Its IUPAC name is prop-2-ynyl 4-methylbenzenesulfonate.

What is Propargyl Tosylate used for?

Propargyl Tosylate is supplied as a characterised reference material related to Rasagiline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Propargyl Tosylate can I order?

We supply Propargyl Tosylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Propargyl Tosylate?

Yes. Every lot of Propargyl Tosylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Propargyl Tosylate be shipped internationally?

Yes. Propargyl Tosylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.