3-Ethoxy-acryloyl chloride

Name: 3-Ethoxy-acryloyl chloride
Brand: Vaqora Chemicals
SKU: VQ-047962

About 3-Ethoxy-acryloyl chloride

3-Ethoxy-acryloyl chloride (CAS 6191-99-7) is a process intermediate or related compound of Dasatinib offered by Vaqora Chemicals. With the molecular formula C5H7ClO2, it has a molar mass of 134.56 g/mol. The IUPAC name is (E)-3-ethoxyprop-2-enoyl chloride. Alternative names: (2E)-3-ethoxyprop-2-enoyl chloride and 2-Propenoyl chloride, 3-ethoxy-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Dasatinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 3-Ethoxy-acryloyl chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Ethoxy-acryloyl chloride
Catalogue No.	VQ-047962
CAS Number	6191-99-7
IUPAC name	(E)-3-ethoxyprop-2-enoyl chloride
Molecular formula	C₅H₇ClO₂
Molecular weight	134.56 g/mol
Exact mass	134.0135
InChIKey	SFMFACMIOWQIPR-ONEGZZNKSA-N
SMILES	CCO/C=C/C(=O)Cl
PubChem CID	5325500

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	(2E)-3-ethoxyprop-2-enoyl chloride, 2-Propenoyl chloride, 3-ethoxy-, Trans-3-Ethoxypropenoyl chloride, 3-ethoxyprop-2-enoyl chloride, 2-Propenoyl chloride, 3-ethoxy-, (2E)-, beta-ethoxyacrylic chloride, beta-ethoxyacrylic acid chloride, (e)-3-ethoxy-2-propenoyl chloride, Acryloyl chloride, 3-ethoxy-, trans-3-ethoxyacryloyl chloride, (E)-3-ethoxy-acryloyl chloride

Safety & hazard information (GHS)

Flammable

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P354 + P338, P316, P321, P330

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Ethoxy-acryloyl chloride?

The CAS Registry Number of 3-Ethoxy-acryloyl chloride is 6191-99-7. It is also known as (2E)-3-ethoxyprop-2-enoyl chloride, 2-Propenoyl chloride, 3-ethoxy-, Trans-3-Ethoxypropenoyl chloride.

What is the molecular formula and molecular weight of 3-Ethoxy-acryloyl chloride?

3-Ethoxy-acryloyl chloride has the molecular formula C5H7ClO2 and a molecular weight of 134.56 g/mol. Its IUPAC name is (E)-3-ethoxyprop-2-enoyl chloride.

What is 3-Ethoxy-acryloyl chloride used for?

3-Ethoxy-acryloyl chloride is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Ethoxy-acryloyl chloride can I order?

We supply 3-Ethoxy-acryloyl chloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Ethoxy-acryloyl chloride?

Yes. Every lot of 3-Ethoxy-acryloyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Ethoxy-acryloyl chloride be shipped internationally?

Yes. 3-Ethoxy-acryloyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.