4,4`-Bis(hydroxyphenyl)methane

Name: 4,4`-Bis(hydroxyphenyl)methane
Brand: Vaqora Chemicals
SKU: VQ-047596

About 4,4`-Bis(hydroxyphenyl)methane

4,4`-Bis(hydroxyphenyl)methane (CAS 620-92-8) is a metabolite or degradation product of Bisoprolol offered by Vaqora Chemicals. Formula C13H12O2, molecular weight 200.23 g/mol. The IUPAC name is 4-[(4-hydroxyphenyl)methyl]phenol. It is also known as Bisphenol F or 4,4'-Methylenediphenol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bisoprolol, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 4,4`-Bis(hydroxyphenyl)methane in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bisoprolol

View every impurity, metabolite and intermediate we list for Bisoprolol.

Bisoprolol impurities

Specifications & identifiers

Chemical identifiers
Product name	4,4`-Bis(hydroxyphenyl)methane
Catalogue No.	VQ-047596
CAS Number	620-92-8
IUPAC name	4-[(4-hydroxyphenyl)methyl]phenol
Molecular formula	C₁₃H₁₂O₂
Molecular weight	200.23 g/mol
Exact mass	200.0837
Grade	Reference Standard
HSN code	38229090
InChIKey	PXKLMJQFEQBVLD-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CC2=CC=C(C=C2)O)O
PubChem CID	12111

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	Bisphenol F, 4,4'-Methylenediphenol, 4,4'-Dihydroxydiphenylmethane, Bis(4-hydroxyphenyl)methane, Phenol, 4,4'-methylenebis-, p-(p-Hydroxybenzyl)phenol, Phenol, 4,4'-methylenedi-, 4,4'-Methylenebisphenol, 4,4'-bisphenol F, p,p'-Bis(hydroxyphenyl)methane, 4,4'-Methylene diphenol

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P271, P272, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,4`-Bis(hydroxyphenyl)methane?

The CAS Registry Number of 4,4`-Bis(hydroxyphenyl)methane is 620-92-8. It is also known as Bisphenol F, 4,4'-Methylenediphenol, 4,4'-Dihydroxydiphenylmethane.

What is the molecular formula and molecular weight of 4,4`-Bis(hydroxyphenyl)methane?

4,4`-Bis(hydroxyphenyl)methane has the molecular formula C13H12O2 and a molecular weight of 200.23 g/mol. Its IUPAC name is 4-[(4-hydroxyphenyl)methyl]phenol.

What is 4,4`-Bis(hydroxyphenyl)methane used for?

4,4`-Bis(hydroxyphenyl)methane is supplied as a characterised reference material related to Bisoprolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,4`-Bis(hydroxyphenyl)methane can I order?

We supply 4,4`-Bis(hydroxyphenyl)methane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,4`-Bis(hydroxyphenyl)methane?

Yes. Every lot of 4,4`-Bis(hydroxyphenyl)methane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,4`-Bis(hydroxyphenyl)methane be shipped internationally?

Yes. 4,4`-Bis(hydroxyphenyl)methane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.