4,6-Dichloro-2-hydroxypyrimidine

Name: 4,6-Dichloro-2-hydroxypyrimidine
Brand: Vaqora Chemicals
SKU: VQ-045394

About 4,6-Dichloro-2-hydroxypyrimidine

Listed under CAS 6297-80-9, 4,6-Dichloro-2-hydroxypyrimidine is an impurity of Fluorouracil available from Vaqora Chemicals. Its molecular formula is C4H2Cl2N2O and its molecular weight is 164.97 g/mol. The IUPAC name is 4,6-dichloro-1H-pyrimidin-2-one. Alternative names: 4,6-dichloropyrimidin-2(1h)-one and 4,6-Dichloropyrimidin-2-ol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Fluorouracil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fluorouracil

View every impurity, metabolite and intermediate we list for Fluorouracil.

Fluorouracil impurities

Specifications & identifiers

Chemical identifiers
Product name	4,6-Dichloro-2-hydroxypyrimidine
Catalogue No.	VQ-045394
CAS Number	6297-80-9
IUPAC name	4,6-dichloro-1H-pyrimidin-2-one
Molecular formula	C₄H₂Cl₂N₂O
Molecular weight	164.97 g/mol
Exact mass	163.9544
Grade	Reference Standard
HSN code	38229090
InChIKey	YFUDLRFOGLVNNA-UHFFFAOYSA-N
SMILES	C1=C(NC(=O)N=C1Cl)Cl
PubChem CID	239924

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 1
TPSA	41.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,6-Dichloro-2-hydroxypyrimidine?

The CAS Registry Number of 4,6-Dichloro-2-hydroxypyrimidine is 6297-80-9. It is also known as 4,6-dichloropyrimidin-2(1h)-one, 4,6-Dichloropyrimidin-2-ol, 2(1H)-Pyrimidinone, 4,6-dichloro-.

What is the molecular formula and molecular weight of 4,6-Dichloro-2-hydroxypyrimidine?

4,6-Dichloro-2-hydroxypyrimidine has the molecular formula C4H2Cl2N2O and a molecular weight of 164.97 g/mol. Its IUPAC name is 4,6-dichloro-1H-pyrimidin-2-one.

What is 4,6-Dichloro-2-hydroxypyrimidine used for?

4,6-Dichloro-2-hydroxypyrimidine is supplied as a characterised reference material related to Fluorouracil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,6-Dichloro-2-hydroxypyrimidine can I order?

We supply 4,6-Dichloro-2-hydroxypyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,6-Dichloro-2-hydroxypyrimidine?

Yes. Every lot of 4,6-Dichloro-2-hydroxypyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,6-Dichloro-2-hydroxypyrimidine be shipped internationally?

Yes. 4,6-Dichloro-2-hydroxypyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.