Sapropterin

Name: Sapropterin
Brand: Vaqora Chemicals
SKU: VQ-033760

About Sapropterin

Vaqora Chemicals supplies Sapropterin, a high-purity reference standard of Sapropterin registered under CAS number 62989-33-7. With the molecular formula C9H15N5O3, it has a molar mass of 241.25 g/mol. Its systematic (IUPAC) name is (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one. Alternative names: Sapropterin S Isomer and R-THBP.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Sapropterin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sapropterin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sapropterin

View every impurity, metabolite and intermediate we list for Sapropterin.

Sapropterin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sapropterin
Catalogue No.	VQ-033760
CAS Number	62989-33-7
IUPAC name	(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one
Molecular formula	C₉H₁₅N₅O₃
Molecular weight	241.25 g/mol
Exact mass	241.1175
Grade	Reference Standard
HSN code	38229090
InChIKey	FNKQXYHWGSIFBK-RPDRRWSUSA-N
SMILES	C[C@@H]([C@@H]([C@H]1CNC2=C(N1)C(=O)NC(=N2)N)O)O
PubChem CID	135398654

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.9
H-bond donors / acceptors	6 / 6
TPSA	132 Å²
Synonyms	Sapropterin S Isomer, R-THBP, Dapropterin, 6R-BH4, (6R)-L-erythro-tetrahydrobiopterin, 6R-5,6,7,8-Tetrahydrobiopterin, 6R-L-5,6,7,8-Tetrahydrobiopterin, sapropterine, (6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin, (-)-(6R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone, (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one, (6R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sapropterin?

The CAS Registry Number of Sapropterin is 62989-33-7. It is also known as Sapropterin S Isomer, R-THBP, Dapropterin.

What is the molecular formula and molecular weight of Sapropterin?

Sapropterin has the molecular formula C9H15N5O3 and a molecular weight of 241.25 g/mol. Its IUPAC name is (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one.

What is Sapropterin used for?

Sapropterin is supplied as a characterised reference material related to Sapropterin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sapropterin can I order?

We supply Sapropterin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sapropterin?

Yes. Every lot of Sapropterin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sapropterin be shipped internationally?

Yes. Sapropterin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.