Nicotine-N-Oxide

Name: Nicotine-N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-007208

About Nicotine-N-Oxide

Listed under CAS 63551-14-4, Nicotine-N-Oxide is a metabolite or degradation product of Nicotine available from Vaqora Chemicals. The compound has the formula C10H14N2O, corresponding to a molecular weight of 178.23 g/mol. Systematically, it is named 3-(1-methyl-1-oxidopyrrolidin-1-ium-2-yl)pyridine. Alternative names: Nicotine 1-N-oxide and Nicotine-1'-oxide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Nicotine, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Nicotine-N-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Nicotine

View every impurity, metabolite and intermediate we list for Nicotine.

Nicotine impurities

Specifications & identifiers

Chemical identifiers
Product name	Nicotine-N-Oxide
Catalogue No.	VQ-007208
CAS Number	63551-14-4
Other CAS	491-26-9
IUPAC name	3-(1-methyl-1-oxidopyrrolidin-1-ium-2-yl)pyridine
Molecular formula	C₁₀H₁₄N₂O
Molecular weight	178.23 g/mol
Exact mass	178.1106
Grade	Reference Standard
HSN code	38229090
InChIKey	RWFBQHICRCUQJJ-UHFFFAOYSA-N
SMILES	C[N+]1(CCCC1C2=CN=CC=C2)[O-]
PubChem CID	409

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	0 / 2
TPSA	31 Å²
Synonyms	1-Methyl-2-(pyridin-3-yl)pyrrolidin-1-ium-1-olate, Nicotine 1-N-oxide, Nicotine-1'-oxide, 3-(1-Methyl-1-oxido-2-pyrrolidinyl)pyridine, 3-(1-Methyl-2-pyrrolidinyl)pyridine, N-oxide, nicotine N(1')-oxide, 1-methyl-2-(3-pyridyl)pyrrolidine 1-oxide, 3-(1-methyl-1-oxidopyrrolidin-2-yl)pyridine, 1-methyl-2-(3-pyridyl)-2,3,4,5-tetrahydropyrrol-1-olate, (-)-Nicotine 1'-oxide, (1's,2's)-Nicotine-N'-oxide, Oxynicotin

Safety & hazard information (GHS)

Corrosive

Toxic

Environmental hazard

Signal word: Danger

Hazard statements

H300+H310+H330Fatal if swallowed, in contact with skin or if inhaled
H300Fatal if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H330Fatal if inhaled
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P262, P264, P264 + P265, P270, P271, P273, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P316, P317, P320, P321, P330, P332 + P317, P361 + P364, P362 + P364, P391, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nicotine-N-Oxide?

The CAS Registry Number of Nicotine-N-Oxide is 63551-14-4. It is also known as 1-Methyl-2-(pyridin-3-yl)pyrrolidin-1-ium-1-olate, Nicotine 1-N-oxide, Nicotine-1'-oxide.

What is the molecular formula and molecular weight of Nicotine-N-Oxide?

Nicotine-N-Oxide has the molecular formula C10H14N2O and a molecular weight of 178.23 g/mol. Its IUPAC name is 3-(1-methyl-1-oxidopyrrolidin-1-ium-2-yl)pyridine.

What is Nicotine-N-Oxide used for?

Nicotine-N-Oxide is supplied as a characterised reference material related to Nicotine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nicotine-N-Oxide can I order?

We supply Nicotine-N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nicotine-N-Oxide?

Yes. Every lot of Nicotine-N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nicotine-N-Oxide be shipped internationally?

Yes. Nicotine-N-Oxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.