Des-Acetyl Apremilast

Name: Des-Acetyl Apremilast
Brand: Vaqora Chemicals
SKU: VQ-007129

About Des-Acetyl Apremilast

Des-Acetyl Apremilast (CAS 635705-72-5) is a metabolite or degradation product of Apremilast offered by Vaqora Chemicals. Formula C20H22N2O6S, molecular weight 418.5 g/mol. Systematically, it is named 4-amino-2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione. Common synonyms include Desacetyl Apremilast and N-Deacetyl apremilast.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Apremilast, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	Des-Acetyl Apremilast
Catalogue No.	VQ-007129
CAS Number	635705-72-5
IUPAC name	4-amino-2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione
Molecular formula	C₂₀H₂₂N₂O₆S
Molecular weight	418.5 g/mol
Exact mass	418.1199
Grade	Reference Standard
HSN code	38229090
InChIKey	BHJUWEUNUCJYER-OAHLLOKOSA-N
SMILES	CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)N)OC
PubChem CID	66718706

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 7
TPSA	124 Å²
Synonyms	(S)-4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione, Desacetyl Apremilast, N-Deacetyl apremilast, Apremilast (m7), (S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione, N-Desacetylapremilast (M7), (S)-4-amino-2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-isoindole-1,3-dione, (1S)-4-amino-2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-isoindole-1,3-dione, 2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-4-aminoisoindoline-1,3-dione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Des-Acetyl Apremilast?

The CAS Registry Number of Des-Acetyl Apremilast is 635705-72-5. It is also known as (S)-4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione, Desacetyl Apremilast, N-Deacetyl apremilast.

What is the molecular formula and molecular weight of Des-Acetyl Apremilast?

Des-Acetyl Apremilast has the molecular formula C20H22N2O6S and a molecular weight of 418.5 g/mol. Its IUPAC name is 4-amino-2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione.

What is Des-Acetyl Apremilast used for?

Des-Acetyl Apremilast is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Des-Acetyl Apremilast can I order?

We supply Des-Acetyl Apremilast in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Des-Acetyl Apremilast?

Yes. Every lot of Des-Acetyl Apremilast is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Des-Acetyl Apremilast be shipped internationally?

Yes. We export Des-Acetyl Apremilast worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.