4-Amino-3-chloro-5-methyl-benzenesulfonic acid 6387-14-0

Name: 4-Amino-3-chloro-5-methyl-benzenesulfonic acid
Brand: Vaqora Chemicals
SKU: VQ-036577

About 4-Amino-3-chloro-5-methyl-benzenesulfonic acid

4-Amino-3-chloro-5-methyl-benzenesulfonic acid is an impurity of Dasatinib carrying the CAS registry number 6387-14-0. Formula C7H8ClNO3S, molecular weight 221.66 g/mol. It is also known as 6-Amino-5-chlorotoluene-3-sulphonic acid or 4-Amino-5-chloro-m-toluensulfonic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Dasatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Amino-3-chloro-5-methyl-benzenesulfonic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dasatinib

View every impurity, metabolite and intermediate we list for Dasatinib.

Dasatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-3-chloro-5-methyl-benzenesulfonic acid
Catalogue No.	VQ-036577
CAS Number	6387-14-0
IUPAC name	4-amino-3-chloro-5-methylbenzenesulfonic acid
Molecular formula	C₇H₈ClNO₃S
Molecular weight	221.66 g/mol
Exact mass	220.9913
Grade	Reference Standard
HSN code	38229090
InChIKey	DTQVHBIQMCFTSZ-UHFFFAOYSA-N
SMILES	CC1=CC(=CC(=C1N)Cl)S(=O)(=O)O
PubChem CID	80802

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	2 / 4
TPSA	88.8 Å²
Synonyms	Benzenesulfonic acid, 4-amino-3-chloro-5-methyl-, 6-Amino-5-chlorotoluene-3-sulphonic acid, 4-Amino-5-chloro-m-toluensulfonic acid, m-Toluenesulfonic acid, 4-amino-5-chloro-, m-Toluenesulfonic acid, 4-amino-5-chloro-(8CI), 4-amino-3-chloro-5-methylbenzene-1-sulfonic acid, 4-amino-5-chloro-m-toluenesulfonic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-3-chloro-5-methyl-benzenesulfonic acid?

The CAS Registry Number of 4-Amino-3-chloro-5-methyl-benzenesulfonic acid is 6387-14-0. It is also known as Benzenesulfonic acid, 4-amino-3-chloro-5-methyl-, 6-Amino-5-chlorotoluene-3-sulphonic acid, 4-Amino-5-chloro-m-toluensulfonic acid.

What is the molecular formula and molecular weight of 4-Amino-3-chloro-5-methyl-benzenesulfonic acid?

4-Amino-3-chloro-5-methyl-benzenesulfonic acid has the molecular formula C7H8ClNO3S and a molecular weight of 221.66 g/mol. Its IUPAC name is 4-amino-3-chloro-5-methylbenzenesulfonic acid.

What is 4-Amino-3-chloro-5-methyl-benzenesulfonic acid used for?

4-Amino-3-chloro-5-methyl-benzenesulfonic acid is supplied as a characterised reference material related to Dasatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-3-chloro-5-methyl-benzenesulfonic acid can I order?

We supply 4-Amino-3-chloro-5-methyl-benzenesulfonic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-3-chloro-5-methyl-benzenesulfonic acid?

Yes. Every lot of 4-Amino-3-chloro-5-methyl-benzenesulfonic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-3-chloro-5-methyl-benzenesulfonic acid be shipped internationally?

Yes. 4-Amino-3-chloro-5-methyl-benzenesulfonic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.