6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione
Synonyms: 7,8-Dehydro-9,10-desacetyldoxorubicinone · 7,8-Dhda-DR · 5,12-Naphthacenedione, 6,8,11-trihydroxy-1-methoxy- · 6,8,11-trihydroxy-1-methoxy-tetracene-5,12-dione
6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione (CAS 64845-67-6) – Doxorubicin impurity standard. C19H12O6, MW 336.3. With COA, ships worldwide.
About 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione
Vaqora Chemicals supplies 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione, an impurity of Doxorubicin registered under CAS number 64845-67-6. With the molecular formula C19H12O6, it has a molar mass of 336.3 g/mol. The IUPAC name is 6,8,11-trihydroxy-1-methoxytetracene-5,12-dione. Common synonyms include 7,8-Dehydro-9,10-desacetyldoxorubicinone and 7,8-Dhda-DR.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
As a characterised impurity of Doxorubicin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Doxorubicin.
Doxorubicin impuritiesSpecifications & identifiers
| Product name | 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione |
|---|---|
| Catalogue No. | VQ-030090 |
| CAS Number | 64845-67-6 |
| IUPAC name | 6,8,11-trihydroxy-1-methoxytetracene-5,12-dione |
| Molecular formula | C19H12O6 |
| Molecular weight | 336.3 g/mol |
| Exact mass | 336.0634 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | HVWINTHXQUZYHP-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC2=C1C(=O)C3=C(C4=C(C=C(C=C4)O)C(=C3C2=O)O)O |
| PubChem CID | 125152 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 4.1 |
| H-bond donors / acceptors | 3 / 6 |
| TPSA | 104 Ų |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowed
Precautionary statements: P264, P270, P301 + P317, P330, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione?
The CAS Registry Number of 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione is 64845-67-6. It is also known as 7,8-Dehydro-9,10-desacetyldoxorubicinone, 7,8-Dhda-DR, 5,12-Naphthacenedione, 6,8,11-trihydroxy-1-methoxy-.
What is the molecular formula and molecular weight of 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione?
6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione has the molecular formula C19H12O6 and a molecular weight of 336.3 g/mol. Its IUPAC name is 6,8,11-trihydroxy-1-methoxytetracene-5,12-dione.
What is 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione used for?
6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione is supplied as a characterised reference material related to Doxorubicin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione can I order?
We supply 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione?
Yes. Every lot of 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione be shipped internationally?
Yes. 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione
We reply within one business day with price, pack options, lead time and documentation.
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