4-Nitrosobenzenamine

Name: 4-Nitrosobenzenamine
Brand: Vaqora Chemicals
SKU: VQ-040537

About 4-Nitrosobenzenamine

4-Nitrosobenzenamine (CAS 659-49-4) is a nitrosamine impurity of Aniline offered by Vaqora Chemicals. Formula C6H6N2O, molecular weight 122.12 g/mol. Its systematic (IUPAC) name is 4-nitrosoaniline. Common synonyms include p-nitrosoaniline and Benzenamine, 4-nitroso-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Nitrosobenzenamine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Aniline

View every impurity, metabolite and intermediate we list for Aniline.

Aniline impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Nitrosobenzenamine
Catalogue No.	VQ-040537
CAS Number	659-49-4
IUPAC name	4-nitrosoaniline
Molecular formula	C₆H₆N₂O
Molecular weight	122.12 g/mol
Exact mass	122.048
Grade	Reference Standard
HSN code	38229090
InChIKey	SALQMMXSINGXMI-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1N)N=O
PubChem CID	69574

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 3
TPSA	55.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Nitrosobenzenamine?

The CAS Registry Number of 4-Nitrosobenzenamine is 659-49-4. It is also known as p-nitrosoaniline, Benzenamine, 4-nitroso-, p-Aminonitrosobenzene.

What is the molecular formula and molecular weight of 4-Nitrosobenzenamine?

4-Nitrosobenzenamine has the molecular formula C6H6N2O and a molecular weight of 122.12 g/mol. Its IUPAC name is 4-nitrosoaniline.

What is 4-Nitrosobenzenamine used for?

4-Nitrosobenzenamine is supplied as a characterised reference material related to Aniline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Nitrosobenzenamine can I order?

We supply 4-Nitrosobenzenamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Nitrosobenzenamine?

Yes. Every lot of 4-Nitrosobenzenamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Nitrosobenzenamine be shipped internationally?

Yes. 4-Nitrosobenzenamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.