4-Hydroxy Duloxetine

Name: 4-Hydroxy Duloxetine
Brand: Vaqora Chemicals
SKU: VQ-048113

About 4-Hydroxy Duloxetine

4-Hydroxy Duloxetine (CAS 662149-13-5) is a metabolite or degradation product of Duloxetine offered by Vaqora Chemicals. With the molecular formula C18H19NO2S, it has a molar mass of 313.4 g/mol. Systematically, it is named 4-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-ol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Duloxetine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-Hydroxy Duloxetine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Duloxetine
Catalogue No.	VQ-048113
CAS Number	662149-13-5
IUPAC name	4-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-ol
Molecular formula	C₁₈H₁₉NO₂S
Molecular weight	313.4 g/mol
Exact mass	313.1137
Grade	Reference Standard
HSN code	38229090
InChIKey	DRRXQCXSBONKPD-KRWDZBQOSA-N
SMILES	CNCC[C@@H](C1=CC=CS1)OC2=CC=C(C3=CC=CC=C32)O
PubChem CID	29981497

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 4
TPSA	69.7 Å²
Synonyms	4-((1S)-3-(Methylamino)-1-(2-thienyl)propoxy)-1-naphthalenol, 4-[(1S)-3-(Methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-ol, 4-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-1-naphthol, 4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalen-1-ol, 4-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]naphthalen-1-ol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Duloxetine?

The CAS Registry Number of 4-Hydroxy Duloxetine is 662149-13-5. It is also known as 4-((1S)-3-(Methylamino)-1-(2-thienyl)propoxy)-1-naphthalenol, 4-[(1S)-3-(Methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-ol, 4-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-1-naphthol.

What is the molecular formula and molecular weight of 4-Hydroxy Duloxetine?

4-Hydroxy Duloxetine has the molecular formula C18H19NO2S and a molecular weight of 313.4 g/mol. Its IUPAC name is 4-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-ol.

What is 4-Hydroxy Duloxetine used for?

4-Hydroxy Duloxetine is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Duloxetine can I order?

We supply 4-Hydroxy Duloxetine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Duloxetine?

Yes. Every lot of 4-Hydroxy Duloxetine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Duloxetine be shipped internationally?

Yes. 4-Hydroxy Duloxetine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.