N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide
Synonyms: 4-[2-[[(5-Methyl-2-pyrazinyl)carbonyl]amino]ethyl]benzenesulfonyl chloride · N-[2-[4-(chlorosulfonyl)phenyl]ethyl]-5-methyl pyrazine-carboxamide · 4-{2-[(5-Methylpyrazine-2-carbonyl)amino]ethyl}benzene-1-sulfonyl chloride
N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide (CAS 66376-00-9) – Glipizide intermediate. C14H14ClN3O3S, MW 339.8. COA included.
About N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide
Listed under CAS 66376-00-9, N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide is a process intermediate or related compound of Glipizide available from Vaqora Chemicals. The compound has the formula C14H14ClN3O3S, corresponding to a molecular weight of 339.8 g/mol. Its systematic (IUPAC) name is 4-[2-[(5-methylpyrazine-2-carbonyl)amino]ethyl]benzenesulfonyl chloride.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.
It is a process intermediate or related compound in the synthesis of Glipizide, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.
Typical applications
- API route development
- Impurity fate & purge studies
- Analytical method development
Industries
View every impurity, metabolite and intermediate we list for Glipizide.
Glipizide impuritiesSpecifications & identifiers
| Product name | N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide |
|---|---|
| Catalogue No. | VQ-013614 |
| CAS Number | 66376-00-9 |
| IUPAC name | 4-[2-[(5-methylpyrazine-2-carbonyl)amino]ethyl]benzenesulfonyl chloride |
| Molecular formula | C14H14ClN3O3S |
| Molecular weight | 339.8 g/mol |
| Exact mass | 339.0444 |
| Grade | Reference Standard |
| HSN code | 2933 |
| InChIKey | GLUACTHHYOSPGO-UHFFFAOYSA-N |
| SMILES | CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)Cl |
| PubChem CID | 22409115 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1 |
| H-bond donors / acceptors | 1 / 5 |
| TPSA | 97.4 Ų |
Documents
Frequently asked questions
What is the CAS number of N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide?
The CAS Registry Number of N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide is 66376-00-9. It is also known as 4-[2-[[(5-Methyl-2-pyrazinyl)carbonyl]amino]ethyl]benzenesulfonyl chloride, N-[2-[4-(chlorosulfonyl)phenyl]ethyl]-5-methyl pyrazine-carboxamide, 4-{2-[(5-Methylpyrazine-2-carbonyl)amino]ethyl}benzene-1-sulfonyl chloride.
What is the molecular formula and molecular weight of N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide?
N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide has the molecular formula C14H14ClN3O3S and a molecular weight of 339.8 g/mol. Its IUPAC name is 4-[2-[(5-methylpyrazine-2-carbonyl)amino]ethyl]benzenesulfonyl chloride.
What is N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide used for?
N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide is supplied as a characterised reference material related to Glipizide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide can I order?
We supply N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide?
Yes. Every lot of N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide be shipped internationally?
Yes. We export N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about N-[2-[4-chlorosulfonylphenyl]ethyl]-5-methylpyrazine carboxamide
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