4-((Tert-Butoxycarbonyl)amino)benzoic acid

Name: 4-((Tert-Butoxycarbonyl)amino)benzoic acid
Brand: Vaqora Chemicals
SKU: VQ-038449

About 4-((Tert-Butoxycarbonyl)amino)benzoic acid

4-((Tert-Butoxycarbonyl)amino)benzoic acid (CAS 66493-39-8) is an impurity of Mitapivat offered by Vaqora Chemicals. The compound has the formula C12H15NO4, corresponding to a molecular weight of 237.25 g/mol. The IUPAC name is 4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid. It is also known as Boc-4-Abz-OH or 4-(Boc-amino)benzoic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Mitapivat, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-((Tert-Butoxycarbonyl)amino)benzoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Mitapivat

View every impurity, metabolite and intermediate we list for Mitapivat.

Mitapivat impurities

Specifications & identifiers

Chemical identifiers
Product name	4-((Tert-Butoxycarbonyl)amino)benzoic acid
Catalogue No.	VQ-038449
CAS Number	66493-39-8
IUPAC name	4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid
Molecular formula	C₁₂H₁₅NO₄
Molecular weight	237.25 g/mol
Exact mass	237.1001
Grade	Reference Standard
HSN code	38229090
InChIKey	ZJDBQMWMDZEONW-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)NC1=CC=C(C=C1)C(=O)O
PubChem CID	2755931

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	Boc-4-Abz-OH, 4-(Boc-amino)benzoic acid, boc-4-aminobenzoic acid, Boc-PABA-OH, 4-(boc-amino)-benzoic acid, N-Boc-4-aminobenzoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-((Tert-Butoxycarbonyl)amino)benzoic acid?

The CAS Registry Number of 4-((Tert-Butoxycarbonyl)amino)benzoic acid is 66493-39-8. It is also known as Boc-4-Abz-OH, 4-(Boc-amino)benzoic acid, boc-4-aminobenzoic acid.

What is the molecular formula and molecular weight of 4-((Tert-Butoxycarbonyl)amino)benzoic acid?

4-((Tert-Butoxycarbonyl)amino)benzoic acid has the molecular formula C12H15NO4 and a molecular weight of 237.25 g/mol. Its IUPAC name is 4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid.

What is 4-((Tert-Butoxycarbonyl)amino)benzoic acid used for?

4-((Tert-Butoxycarbonyl)amino)benzoic acid is supplied as a characterised reference material related to Mitapivat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-((Tert-Butoxycarbonyl)amino)benzoic acid can I order?

We supply 4-((Tert-Butoxycarbonyl)amino)benzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-((Tert-Butoxycarbonyl)amino)benzoic acid?

Yes. Every lot of 4-((Tert-Butoxycarbonyl)amino)benzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-((Tert-Butoxycarbonyl)amino)benzoic acid be shipped internationally?

Yes. 4-((Tert-Butoxycarbonyl)amino)benzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.