Risperidone Hydroxyethyl Impurity

About Risperidone Hydroxyethyl Impurity

Risperidone Hydroxyethyl Impurity is a metabolite or degradation product of Risperidone carrying the CAS registry number 66698-27-9. Its molecular formula is C11H16N2O2 and its molecular weight is 208.26 g/mol. Systematically, it is named 3-(2-hydroxyethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Risperidone, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Risperidone

View every impurity, metabolite and intermediate we list for Risperidone.

Risperidone impurities

Specifications & identifiers

Chemical identifiers
Product name	Risperidone Hydroxyethyl Impurity
Catalogue No.	VQ-027839
CAS Number	66698-27-9
IUPAC name	3-(2-hydroxyethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Molecular formula	C₁₁H₁₆N₂O₂
Molecular weight	208.26 g/mol
Exact mass	208.1212
Grade	Reference Standard
HSN code	38229090
InChIKey	ICDWUCZPFCGGIP-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N2CCCCC2=N1)CCO
PubChem CID	11413127

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 3
TPSA	52.9 Å²
Synonyms	3-(2-Hydroxyethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one, 3-(2-hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one, 3-(2-hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido(1,2-a)pyrimidin-4-one, 3-(2-Hydroxy-ethyl)-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one, 3-(2-Hydroxyethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido-(1,2-a)-pyrimidin-4-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Risperidone Hydroxyethyl Impurity?

The CAS Registry Number of Risperidone Hydroxyethyl Impurity is 66698-27-9. It is also known as 3-(2-Hydroxyethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one, 3-(2-hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one, 3-(2-hydroxyethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido(1,2-a)pyrimidin-4-one.

What is the molecular formula and molecular weight of Risperidone Hydroxyethyl Impurity?

Risperidone Hydroxyethyl Impurity has the molecular formula C11H16N2O2 and a molecular weight of 208.26 g/mol. Its IUPAC name is 3-(2-hydroxyethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one.

What is Risperidone Hydroxyethyl Impurity used for?

Risperidone Hydroxyethyl Impurity is supplied as a characterised reference material related to Risperidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Risperidone Hydroxyethyl Impurity can I order?

We supply Risperidone Hydroxyethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Risperidone Hydroxyethyl Impurity?

Yes. Every lot of Risperidone Hydroxyethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Risperidone Hydroxyethyl Impurity be shipped internationally?

Yes. Risperidone Hydroxyethyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.