Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate 66975-53-9

Name: Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate
Brand: Vaqora Chemicals
SKU: VQ-045028

About Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate

Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate (CAS 66975-53-9) is an impurity of Leflunomide offered by Vaqora Chemicals. Formula C9H14O4, molecular weight 186.2 g/mol. Its systematic (IUPAC) name is ethyl (2Z)-2-(ethoxymethylidene)-3-oxobutanoate. Alternative names: Ethyl-2-ethoxymehyledene-3-oxobutonoate and ethyl 2-(ethoxymethylene)-3-oxobutanoate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Leflunomide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Leflunomide

View every impurity, metabolite and intermediate we list for Leflunomide.

Leflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate
Catalogue No.	VQ-045028
CAS Number	66975-53-9
IUPAC name	ethyl (2Z)-2-(ethoxymethylidene)-3-oxobutanoate
Molecular formula	C₉H₁₄O₄
Molecular weight	186.2 g/mol
Exact mass	186.0892
Grade	Reference Standard
HSN code	38229090
InChIKey	FNASCUBBFNCFQO-VURMDHGXSA-N
SMILES	CCO/C=C(/C(=O)C)\C(=O)OCC
PubChem CID	5355337

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	0 / 4
TPSA	52.6 Å²
Synonyms	Ethyl-2-ethoxymehyledene-3-oxobutonoate, ethyl 2-(ethoxymethylene)-3-oxobutanoate, 2-(Ethoxymethylene)-3-oxobutanoic acid ethyl ester, Ethyl 2-Acetyl-3-ethoxyacrylate, (Z)-Ethyl 2-(ethoxymethylene)-3-oxobutanoate, Butanoic acid, 2-(ethoxymethylene)-3-oxo-, ethyl ester, (2Z)-, Ethyl cis-2-(ethoxymethylene)acetoacetate, (Z)-Ethyl2-(ethoxymethylene)-3-oxobutanoate, ethyl (2Z)-2-acetyl-3-ethoxyprop-2-enoate, ethyl (2Z)-2-(ethoxymethylene)-3-oxo-butanoate, Ethyl (2Z)-2-(ethoxymethylene)-3-oxobutanoate, 2-ETHOXYMETHYLENE-3-OXO-BUTYRIc acid ETHYL ESTER

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate?

The CAS Registry Number of Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate is 66975-53-9. It is also known as Ethyl-2-ethoxymehyledene-3-oxobutonoate, ethyl 2-(ethoxymethylene)-3-oxobutanoate, 2-(Ethoxymethylene)-3-oxobutanoic acid ethyl ester.

What is the molecular formula and molecular weight of Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate?

Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate has the molecular formula C9H14O4 and a molecular weight of 186.2 g/mol. Its IUPAC name is ethyl (2Z)-2-(ethoxymethylidene)-3-oxobutanoate.

What is Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate used for?

Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate is supplied as a characterised reference material related to Leflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate can I order?

We supply Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate?

Yes. Every lot of Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate be shipped internationally?

Yes. We export Ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.