Nitrofurantoin

About Nitrofurantoin

Nitrofurantoin is a high-purity reference standard of Nitrofurantoin carrying the CAS registry number 67-20-9. The compound has the formula C8H6N4O5, corresponding to a molecular weight of 238.16 g/mol. Its systematic (IUPAC) name is 1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione. Alternative names: Furadantin and Macrodantin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Nitrofurantoin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nitrofurantoin

View every impurity, metabolite and intermediate we list for Nitrofurantoin.

Nitrofurantoin impurities

Specifications & identifiers

Chemical identifiers
Product name	Nitrofurantoin
Catalogue No.	VQ-026933
CAS Number	67-20-9
IUPAC name	1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
Molecular formula	C₈H₆N₄O₅
Molecular weight	238.16 g/mol
Exact mass	238.0338
Grade	Reference Standard
HSN code	38229090
InChIKey	NXFQHRVNIOXGAQ-YCRREMRBSA-N
SMILES	C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-]
PubChem CID	6604200

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	1 / 6
TPSA	121 Å²
Synonyms	Furadantin, Macrodantin, 5-Nitrofurantoin, Furadantoin, Furadonin, Furadontin, Nifurantin, Urantoin, Nitrofurantoine, Berkfurin, Furadoine, Furadonine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nitrofurantoin?

The CAS Registry Number of Nitrofurantoin is 67-20-9. It is also known as Furadantin, Macrodantin, 5-Nitrofurantoin.

What is the molecular formula and molecular weight of Nitrofurantoin?

Nitrofurantoin has the molecular formula C8H6N4O5 and a molecular weight of 238.16 g/mol. Its IUPAC name is 1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione.

What is Nitrofurantoin used for?

Nitrofurantoin is supplied as a characterised reference material related to Nitrofurantoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nitrofurantoin can I order?

We supply Nitrofurantoin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nitrofurantoin?

Yes. Every lot of Nitrofurantoin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nitrofurantoin be shipped internationally?

Yes. Nitrofurantoin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.