Alpha-Methyl-L-tyrosine

About Alpha-Methyl-L-tyrosine

Alpha-Methyl-L-tyrosine is a high-purity reference standard of Metyrosine carrying the CAS registry number 672-87-7. The compound has the formula C10H13NO3, corresponding to a molecular weight of 195.21 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid. Alternative names: Metyrosine and Metirosine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Metyrosine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material
Fine chemical synthesis

Industries

Related to Metyrosine

View every impurity, metabolite and intermediate we list for Metyrosine.

Metyrosine impurities

Specifications & identifiers

Chemical identifiers
Product name	Alpha-Methyl-L-tyrosine
Catalogue No.	VQ-034479
CAS Number	672-87-7
IUPAC name	(2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
Molecular formula	C₁₀H₁₃NO₃
Molecular weight	195.21 g/mol
Exact mass	195.0895
Grade	Reference Standard
HSN code	38229090
InChIKey	NHTGHBARYWONDQ-JTQLQIEISA-N
SMILES	C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N
PubChem CID	441350

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.6
H-bond donors / acceptors	3 / 4
TPSA	83.6 Å²
Synonyms	Metyrosine, Metirosine, (S)-alpha-Methyltyrosine, L-alpha-Methyltyrosine, Alpha-Methyl-L-P-Tyrosine, MK-781, methyl-tyrosine, alpha-Methyltyrosine, (L)-, Methyltyrosine, (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid, L-alpha-Methyl-p-tyrosine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H335May cause respiratory irritation

Precautionary statements: P261, P264, P270, P271, P301 + P317, P304 + P340, P319, P330, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alpha-Methyl-L-tyrosine?

The CAS Registry Number of Alpha-Methyl-L-tyrosine is 672-87-7. It is also known as Metyrosine, Metirosine, (S)-alpha-Methyltyrosine.

What is the molecular formula and molecular weight of Alpha-Methyl-L-tyrosine?

Alpha-Methyl-L-tyrosine has the molecular formula C10H13NO3 and a molecular weight of 195.21 g/mol. Its IUPAC name is (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid.

What is Alpha-Methyl-L-tyrosine used for?

Alpha-Methyl-L-tyrosine is supplied as a characterised reference material related to Metyrosine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alpha-Methyl-L-tyrosine can I order?

We supply Alpha-Methyl-L-tyrosine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alpha-Methyl-L-tyrosine?

Yes. Every lot of Alpha-Methyl-L-tyrosine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alpha-Methyl-L-tyrosine be shipped internationally?

Yes. Alpha-Methyl-L-tyrosine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.