(R)-Pyrrolidine-2-carbonitrile Hydrochloride 675602-84-3

About (R)-Pyrrolidine-2-carbonitrile Hydrochloride

(R)-Pyrrolidine-2-carbonitrile Hydrochloride is an impurity of Acetone carrying the CAS registry number 675602-84-3. Its molecular formula is C5H9ClN2 and its molecular weight is 132.59 g/mol. It is also known as (2R)-pyrrolidine-2-carbonitrile Hydrochloride or (r)-2-cyanopyrrolidine hydrochloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Acetone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Pyrrolidine-2-carbonitrile Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acetone

View every impurity, metabolite and intermediate we list for Acetone.

Acetone impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Pyrrolidine-2-carbonitrile Hydrochloride
Catalogue No.	VQ-039094
CAS Number	675602-84-3
IUPAC name	(2R)-pyrrolidine-2-carbonitrile;hydrochloride
Molecular formula	C₅H₉ClN₂
Molecular weight	132.59 g/mol
Exact mass	132.0454
Grade	Reference Standard
HSN code	38229090
InChIKey	QSJTUXCBPTVKQZ-NUBCRITNSA-N
SMILES	C1C[C@@H](NC1)C#N.Cl
PubChem CID	2760525

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 2
TPSA	35.8 Å²
Synonyms	(2R)-pyrrolidine-2-carbonitrile Hydrochloride, (r)-2-cyanopyrrolidine hydrochloride, (R)-Pyrrolidine-2-carbonitrile HCl, (R)-2-Pyrrolidinecarbonitrile hydrochloride, (R)-2-Pyrrolidinecarbonitrile HCl, (2R)-2-Pyrrolidinecarbonitrile, monohydrochloride, (2R)-Pyrrolidine-2-carbonitrile--hydrogen chloride (1/1)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Pyrrolidine-2-carbonitrile Hydrochloride?

The CAS Registry Number of (R)-Pyrrolidine-2-carbonitrile Hydrochloride is 675602-84-3. It is also known as (2R)-pyrrolidine-2-carbonitrile Hydrochloride, (r)-2-cyanopyrrolidine hydrochloride, (R)-Pyrrolidine-2-carbonitrile HCl.

What is the molecular formula and molecular weight of (R)-Pyrrolidine-2-carbonitrile Hydrochloride?

(R)-Pyrrolidine-2-carbonitrile Hydrochloride has the molecular formula C5H9ClN2 and a molecular weight of 132.59 g/mol.

What is (R)-Pyrrolidine-2-carbonitrile Hydrochloride used for?

(R)-Pyrrolidine-2-carbonitrile Hydrochloride is supplied as a characterised reference material related to Acetone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Pyrrolidine-2-carbonitrile Hydrochloride can I order?

We supply (R)-Pyrrolidine-2-carbonitrile Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Pyrrolidine-2-carbonitrile Hydrochloride?

Yes. Every lot of (R)-Pyrrolidine-2-carbonitrile Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Pyrrolidine-2-carbonitrile Hydrochloride be shipped internationally?

Yes. (R)-Pyrrolidine-2-carbonitrile Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.