(E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid 67801-07-4

Name: (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid
Brand: Vaqora Chemicals
SKU: VQ-029812

About (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid

Vaqora Chemicals supplies (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid, an impurity of Cinacalcet registered under CAS number 67801-07-4. Its molecular formula is C10H7F3O2 and its molecular weight is 216.16 g/mol. The IUPAC name is (E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid. It is also known as 3-(Trifluoromethyl)cinnamic acid or (E)-m-(Trifluoromethyl)cinnamic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Cinacalcet to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cinacalcet

View every impurity, metabolite and intermediate we list for Cinacalcet.

Cinacalcet impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid
Catalogue No.	VQ-029812
CAS Number	67801-07-4
IUPAC name	(E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid
Molecular formula	C₁₀H₇F₃O₂
Molecular weight	216.16 g/mol
Exact mass	216.0398
Grade	Reference Standard
HSN code	38229090
InChIKey	KSBWHDDGWSYETA-SNAWJCMRSA-N
SMILES	C1=CC(=CC(=C1)C(F)(F)F)/C=C/C(=O)O
PubChem CID	719451

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	1 / 5
TPSA	37.3 Å²
Synonyms	3-(Trifluoromethyl)cinnamic acid, (E)-m-(Trifluoromethyl)cinnamic acid, m-(trifluoromethyl)cinnamic acid, 3-(3-(Trifluoromethyl)phenyl)acrylic acid, trans-3-(trifluoromethyl)cinnamic acid, 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, (2E)-, 2-Propenoic acid, 3-(3-(trifluoromethyl)phenyl)-, (2E)-3-[3-(Trifluoromethyl)phenyl]-2-propenoic acid, m-(Trifluoromethyl)cinnamic acid, (trans)-, 2-Propenoic acid, 3-(3-(trifluoromethyl)phenyl)-, (2E)-, 3-(3-(Trifluoromethyl)phenyl)-2-propenoic acid, 3-[3-(trifluoromethyl)phenyl]acrylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid?

The CAS Registry Number of (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid is 67801-07-4. It is also known as 3-(Trifluoromethyl)cinnamic acid, (E)-m-(Trifluoromethyl)cinnamic acid, m-(trifluoromethyl)cinnamic acid.

What is the molecular formula and molecular weight of (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid?

(E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid has the molecular formula C10H7F3O2 and a molecular weight of 216.16 g/mol. Its IUPAC name is (E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid.

What is (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid used for?

(E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid is supplied as a characterised reference material related to Cinacalcet. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid can I order?

We supply (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid?

Yes. Every lot of (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid be shipped internationally?

Yes. (E)-3-(3-(Trifluoromethyl)phenyl)acrylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.