Norethindrone Acetate 6-alpha-Hydroxy Impurity 6856-28-6

Name: Norethindrone Acetate 6-alpha-Hydroxy Impurity
Brand: Vaqora Chemicals
SKU: VQ-026951

About Norethindrone Acetate 6-alpha-Hydroxy Impurity

Vaqora Chemicals supplies Norethindrone Acetate 6-alpha-Hydroxy Impurity, a metabolite or degradation product of Norethindrone registered under CAS number 6856-28-6. With the molecular formula C22H28O4, it has a molar mass of 356.5 g/mol. Alternative names: 6α-Hydroxy Norethindrone Acetate and 6a-Hydroxy Norethindrone Acetate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Norethindrone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Norethindrone Acetate 6-alpha-Hydroxy Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Norethindrone

View every impurity, metabolite and intermediate we list for Norethindrone.

Norethindrone impurities

Specifications & identifiers

Chemical identifiers
Product name	Norethindrone Acetate 6-alpha-Hydroxy Impurity
Catalogue No.	VQ-026951
CAS Number	6856-28-6
IUPAC name	[(6S,8R,9S,10R,13S,14S,17R)-17-ethynyl-6-hydroxy-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
Molecular formula	C₂₂H₂₈O₄
Molecular weight	356.5 g/mol
Exact mass	356.1988
Grade	Reference Standard
HSN code	38229090
InChIKey	NVEXGWVOAPQSMX-OARMXLMKSA-N
SMILES	CC(=O)O[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@H]34)O)C)C#C
PubChem CID	71748799

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 4
TPSA	63.6 Å²
Synonyms	6α-Hydroxy Norethindrone Acetate, 6a-Hydroxy Norethindrone Acetate, 6alpha-Hydroxy Norethindrone Acetate, 6alpha-Hydroxynorethisterone Acetate, 6-Hydroxy-norethindroneacetate, 19-NOrpregn-4-en-20-yn-3-one, 17-(acetyloxy)-6-hydroxy-, (6, A,17, A)-, (6alpha,17alpha)-6-Hydroxy-3-oxo-19-norpregn-4-en-20-yn-17-yl acetate, 6alpha-Hydroxy-3-oxo-17alpha-19-norpregn-4-en-20-yn-17-yl acetate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H351Suspected of causing cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P233, P260, P264, P270, P271, P280, P284, P301 + P317, P304 + P340, P318, P330, P342 + P316, P403, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Norethindrone Acetate 6-alpha-Hydroxy Impurity?

The CAS Registry Number of Norethindrone Acetate 6-alpha-Hydroxy Impurity is 6856-28-6. It is also known as 6α-Hydroxy Norethindrone Acetate, 6a-Hydroxy Norethindrone Acetate, 6alpha-Hydroxy Norethindrone Acetate.

What is the molecular formula and molecular weight of Norethindrone Acetate 6-alpha-Hydroxy Impurity?

Norethindrone Acetate 6-alpha-Hydroxy Impurity has the molecular formula C22H28O4 and a molecular weight of 356.5 g/mol. Its IUPAC name is [(6S,8R,9S,10R,13S,14S,17R)-17-ethynyl-6-hydroxy-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate.

What is Norethindrone Acetate 6-alpha-Hydroxy Impurity used for?

Norethindrone Acetate 6-alpha-Hydroxy Impurity is supplied as a characterised reference material related to Norethindrone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Norethindrone Acetate 6-alpha-Hydroxy Impurity can I order?

We supply Norethindrone Acetate 6-alpha-Hydroxy Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Norethindrone Acetate 6-alpha-Hydroxy Impurity?

Yes. Every lot of Norethindrone Acetate 6-alpha-Hydroxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Norethindrone Acetate 6-alpha-Hydroxy Impurity be shipped internationally?

Yes. Norethindrone Acetate 6-alpha-Hydroxy Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.