1-Amino-4-methylpiperazine

Name: 1-Amino-4-methylpiperazine
Brand: Vaqora Chemicals
SKU: VQ-050121

About 1-Amino-4-methylpiperazine

1-Amino-4-methylpiperazine is a process intermediate or related compound of Rifamycin carrying the CAS registry number 6928-85-4. With the molecular formula C5H13N3, it has a molar mass of 115.18 g/mol. The IUPAC name is 4-methylpiperazin-1-amine. It is also known as 4-Methyl-1-piperazinamine or 1-Piperazinamine, 4-methyl-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Rifamycin, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Amino-4-methylpiperazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Rifamycin

View every impurity, metabolite and intermediate we list for Rifamycin.

Rifamycin impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Amino-4-methylpiperazine
Catalogue No.	VQ-050121
CAS Number	6928-85-4
IUPAC name	4-methylpiperazin-1-amine
Molecular formula	C₅H₁₃N₃
Molecular weight	115.18 g/mol
Exact mass	115.1109
HSN code	2933
InChIKey	RJWLLQWLBMJCFD-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)N
PubChem CID	81349

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	1 / 3
TPSA	32.5 Å²
Synonyms	4-Methyl-1-piperazinamine, 1-Piperazinamine, 4-methyl-, 1-methyl-4-aminopiperazine, 1-Methyl-4-aminopierazine, 4-methyl-1-aminopiperazine, 4-amino-1-methylpiperazine, n-amino-n'-methylpiperazine, 4-methylpiperazin-1-ylamine, N1-Methyl-N4-aminopiperazine, (4-methylpiperazin-1-yl)amine, 4-methylpiperazinylamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Amino-4-methylpiperazine?

The CAS Registry Number of 1-Amino-4-methylpiperazine is 6928-85-4. It is also known as 4-Methyl-1-piperazinamine, 1-Piperazinamine, 4-methyl-, 1-methyl-4-aminopiperazine.

What is the molecular formula and molecular weight of 1-Amino-4-methylpiperazine?

1-Amino-4-methylpiperazine has the molecular formula C5H13N3 and a molecular weight of 115.18 g/mol. Its IUPAC name is 4-methylpiperazin-1-amine.

What is 1-Amino-4-methylpiperazine used for?

1-Amino-4-methylpiperazine is supplied as a characterised reference material related to Rifamycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Amino-4-methylpiperazine can I order?

We supply 1-Amino-4-methylpiperazine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Amino-4-methylpiperazine?

Yes. Every lot of 1-Amino-4-methylpiperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Amino-4-methylpiperazine be shipped internationally?

Yes. 1-Amino-4-methylpiperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.