Brivudine

About Brivudine

Brivudine is a high-purity reference standard of Brivudine carrying the CAS registry number 69304-47-8. The compound has the formula C11H13BrN2O5, corresponding to a molecular weight of 333.13 g/mol. Systematically, it is named 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. It is also known as (E)-5-(2-Bromovinyl)-2'-deoxyuridine or Brivudin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Brivudine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Brivudine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Brivudine

View every impurity, metabolite and intermediate we list for Brivudine.

Brivudine impurities

Specifications & identifiers

Chemical identifiers
Product name	Brivudine
Catalogue No.	VQ-024657
CAS Number	69304-47-8
IUPAC name	5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Molecular formula	C₁₁H₁₃BrN₂O₅
Molecular weight	333.13 g/mol
Exact mass	332.0008
Grade	Reference Standard
HSN code	38229090
InChIKey	ODZBBRURCPAEIQ-PIXDULNESA-N
SMILES	C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)/C=C/Br)CO)O
PubChem CID	446727

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	3 / 5
TPSA	99.1 Å²
Synonyms	(E)-5-(2-Bromovinyl)-2'-deoxyuridine, Brivudin, Helpin, (E)-5-(2-Bromovinyl)-deoxyuridine, RP-101, trans-5-(2-Bromovinyl)-2'-deoxyuridine, 5-BVDU, E-5-(2-bromovinyl)-dUrd, Z-5-(2-bromovinyl)-dUrd, 5-(2-bromovinyl)-2'-deoxyuridine, 5-(2-bromoethenyl)-2'-deoxyuridine, bromovinyl-deoxyuridine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Brivudine?

The CAS Registry Number of Brivudine is 69304-47-8. It is also known as (E)-5-(2-Bromovinyl)-2'-deoxyuridine, Brivudin, Helpin.

What is the molecular formula and molecular weight of Brivudine?

Brivudine has the molecular formula C11H13BrN2O5 and a molecular weight of 333.13 g/mol. Its IUPAC name is 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.

What is Brivudine used for?

Brivudine is supplied as a characterised reference material related to Brivudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Brivudine can I order?

We supply Brivudine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brivudine?

Yes. Every lot of Brivudine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brivudine be shipped internationally?

Yes. We export Brivudine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.