(S)-Cinacalcet

Name: (S)-Cinacalcet
Brand: Vaqora Chemicals
SKU: VQ-004276

About (S)-Cinacalcet

(S)-Cinacalcet (CAS 694495-47-1) is an impurity of Cinacalcet offered by Vaqora Chemicals. Formula C22H23ClF3N, molecular weight 393.9 g/mol. Systematically, it is named N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine. Hydrochloride. Common synonyms include ent-Cinacalcet Hydrochloride and (S)-Cinacalcet hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Cinacalcet to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (S)-Cinacalcet in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cinacalcet

View every impurity, metabolite and intermediate we list for Cinacalcet.

Cinacalcet impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Cinacalcet
Catalogue No.	VQ-004276
CAS Number	694495-47-1
IUPAC name	N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Molecular formula	C₂₂H₂₃ClF₃N
Molecular weight	393.9 g/mol
Exact mass	393.1471
Grade	Reference Standard
HSN code	38229090
InChIKey	QANQWUQOEJZMLL-NTISSMGPSA-N
SMILES	C[C@@H](C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
PubChem CID	46781027

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	12 Å²
Synonyms	(αS)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, (S)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, N-((1S)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)-1-propanamine hydrochloride, N-[(1S)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine hydrochloride, ent-Cinacalcet Hydrochloride, (S)-Cinacalcet hydrochloride, (S)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride, ent-Cinacalcet HCl, C22H23ClF3N, ent-CinacalcetHydrochloride, CS-M2645, (S)-N-(1-(Naphthalen-1-yl)eth

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264 + P265, P280, P305 + P351 + P338, P319, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Cinacalcet?

The CAS Registry Number of (S)-Cinacalcet is 694495-47-1. It is also known as (αS)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, (S)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, N-((1S)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)-1-propanamine hydrochloride.

What is the molecular formula and molecular weight of (S)-Cinacalcet?

(S)-Cinacalcet has the molecular formula C22H23ClF3N and a molecular weight of 393.9 g/mol.

What is (S)-Cinacalcet used for?

(S)-Cinacalcet is supplied as a characterised reference material related to Cinacalcet. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Cinacalcet can I order?

We supply (S)-Cinacalcet in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Cinacalcet?

Yes. Every lot of (S)-Cinacalcet is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Cinacalcet be shipped internationally?

Yes. (S)-Cinacalcet is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.