Linagliptin Nitroso Pyrimidine Impurity

Name: Linagliptin Nitroso Pyrimidine Impurity
Brand: Vaqora Chemicals
SKU: VQ-026478

About Linagliptin Nitroso Pyrimidine Impurity

Vaqora Chemicals supplies Linagliptin Nitroso Pyrimidine Impurity, a nitrosamine impurity of Linagliptin registered under CAS number 6972-78-7. Formula C5H6N4O3, molecular weight 170.13 g/mol. Its systematic (IUPAC) name is 6-amino-1-methyl-5-nitrosopyrimidine-2,4-dione. It is also known as Nitroso Linagliptin or 6-Amino-1-methyl-5-nitrosouracil.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Linagliptin, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Linagliptin Nitroso Pyrimidine Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Linagliptin Nitroso Pyrimidine Impurity
Catalogue No.	VQ-026478
CAS Number	6972-78-7
IUPAC name	6-amino-1-methyl-5-nitrosopyrimidine-2,4-dione
Molecular formula	C₅H₆N₄O₃
Molecular weight	170.13 g/mol
Exact mass	170.044
Grade	Reference Standard
HSN code	38229090
InChIKey	AHOWVSJPUQTRNN-UHFFFAOYSA-N
SMILES	CN1C(=C(C(=O)NC1=O)N=O)N
PubChem CID	81448

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	2 / 5
TPSA	105 Å²
Synonyms	Nitroso Linagliptin, 6-Amino-1-methyl-5-nitrosouracil, 6-amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione, 6-amino-1-methyl-5-nitrosopyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione,6-amino-1-methyl-5-nitroso-, 2,4(1H,3H)-Pyrimidinedione, 6-amino-1-methyl-5-nitroso-, 6-amino-1-methyl-5-nitroso-1,2,3,4-tetrahydropyrimidine-2,4-dione, 6-amino-1-methyl-5-nitroso-1,3-dihydropyrimidine-2,4-dione, 6-amino-1-methyl-5-nitroso-pyrimidine-2,4-dione, 6-Amino-1-methyl-5-nitroso-1H-pyrimidine-2,4-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Linagliptin Nitroso Pyrimidine Impurity?

The CAS Registry Number of Linagliptin Nitroso Pyrimidine Impurity is 6972-78-7. It is also known as Nitroso Linagliptin, 6-Amino-1-methyl-5-nitrosouracil, 6-amino-1-methyl-5-nitroso-2,4(1H,3H)-pyrimidinedione.

What is the molecular formula and molecular weight of Linagliptin Nitroso Pyrimidine Impurity?

Linagliptin Nitroso Pyrimidine Impurity has the molecular formula C5H6N4O3 and a molecular weight of 170.13 g/mol. Its IUPAC name is 6-amino-1-methyl-5-nitrosopyrimidine-2,4-dione.

What is Linagliptin Nitroso Pyrimidine Impurity used for?

Linagliptin Nitroso Pyrimidine Impurity is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Linagliptin Nitroso Pyrimidine Impurity can I order?

We supply Linagliptin Nitroso Pyrimidine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Linagliptin Nitroso Pyrimidine Impurity?

Yes. Every lot of Linagliptin Nitroso Pyrimidine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Linagliptin Nitroso Pyrimidine Impurity be shipped internationally?

Yes. Linagliptin Nitroso Pyrimidine Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.