Trifluridine

Name: Trifluridine
Brand: Vaqora Chemicals
SKU: VQ-007819

About Trifluridine

Trifluridine (CAS 70-00-8) is a high-purity reference standard of Trifluridine offered by Vaqora Chemicals. Formula C10H11F3N2O5, molecular weight 296.2 g/mol. Its systematic (IUPAC) name is 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione. Common synonyms include α,α,α-Trifluorothymidine and 2′-Deoxy-5-(trifluoromethyl)uridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Trifluridine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Trifluridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Trifluridine

View every impurity, metabolite and intermediate we list for Trifluridine.

Trifluridine impurities

Specifications & identifiers

Chemical identifiers
Product name	Trifluridine
Catalogue No.	VQ-007819
CAS Number	70-00-8
IUPAC name	1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione
Molecular formula	C₁₀H₁₁F₃N₂O₅
Molecular weight	296.2 g/mol
Exact mass	296.062
Grade	Reference Standard
HSN code	38229090
InChIKey	VSQQQLOSPVPRAZ-RRKCRQDMSA-N
SMILES	C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O
PubChem CID	6256

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	3 / 8
TPSA	99.1 Å²
Synonyms	α,α,α-Trifluorothymidine, 2′-Deoxy-5-(trifluoromethyl)uridine, 5-(Trifluoromethyl)-2′-deoxyuridine, 5-(Trifluoromethyl)deoxyuridine, 5-Trifluoromethyl-2′-deoxy-β-uridine, 5-Trifluorothymidine, Trifluorothymidine, Viroptic, F3DThd, Trifluoromethyldeoxyuridine, F3TDR, 5-Trifluoromethyl-2-deoxyuridine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trifluridine?

The CAS Registry Number of Trifluridine is 70-00-8. It is also known as α,α,α-Trifluorothymidine, 2′-Deoxy-5-(trifluoromethyl)uridine, 5-(Trifluoromethyl)-2′-deoxyuridine.

What is the molecular formula and molecular weight of Trifluridine?

Trifluridine has the molecular formula C10H11F3N2O5 and a molecular weight of 296.2 g/mol. Its IUPAC name is 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione.

What is Trifluridine used for?

Trifluridine is supplied as a characterised reference material related to Trifluridine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trifluridine can I order?

We supply Trifluridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trifluridine?

Yes. Every lot of Trifluridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trifluridine be shipped internationally?

Yes. Trifluridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.