2-Hydroxy-thiobenzamide

Name: 2-Hydroxy-thiobenzamide
Brand: Vaqora Chemicals
SKU: VQ-049673

About 2-Hydroxy-thiobenzamide

Listed under CAS 7133-90-6, 2-Hydroxy-thiobenzamide is a metabolite or degradation product of Febuxostat available from Vaqora Chemicals. With the molecular formula C7H7NOS, it has a molar mass of 153.2 g/mol. The IUPAC name is 2-hydroxybenzenecarbothioamide. Common synonyms include 2-Hydroxybenzothioamide and 2-hydroxybenzene-1-carbothioamide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Febuxostat, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Hydroxy-thiobenzamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Febuxostat

View every impurity, metabolite and intermediate we list for Febuxostat.

Febuxostat impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy-thiobenzamide
Catalogue No.	VQ-049673
CAS Number	7133-90-6
IUPAC name	2-hydroxybenzenecarbothioamide
Molecular formula	C₇H₇NOS
Molecular weight	153.2 g/mol
Exact mass	153.0248
Grade	Reference Standard
HSN code	38229090
InChIKey	JFYIBFCXQUDFQE-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)C(=S)N)O
PubChem CID	2759342

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 2
TPSA	78.3 Å²
Synonyms	2-Hydroxybenzothioamide, 2-hydroxybenzene-1-carbothioamide, Thiosalicylamide, Salicylamide, thio-, 2-Hydroxybenzothiamide, Benzenecarbothioamide,2-hydroxy-, Benzenecarbothioamide, 2-hydroxy-, 2-(aminothioxomethyl)phenol, 2-Hydroxybenzenecarbothioamide #, (6E)-6-[amino(sulfanyl)methylidene]cyclohexa-2,4-dien-1-one, 2-hydroxybenzenecarboximidothioic acid

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P317, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy-thiobenzamide?

The CAS Registry Number of 2-Hydroxy-thiobenzamide is 7133-90-6. It is also known as 2-Hydroxybenzothioamide, 2-hydroxybenzene-1-carbothioamide, Thiosalicylamide.

What is the molecular formula and molecular weight of 2-Hydroxy-thiobenzamide?

2-Hydroxy-thiobenzamide has the molecular formula C7H7NOS and a molecular weight of 153.2 g/mol. Its IUPAC name is 2-hydroxybenzenecarbothioamide.

What is 2-Hydroxy-thiobenzamide used for?

2-Hydroxy-thiobenzamide is supplied as a characterised reference material related to Febuxostat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy-thiobenzamide can I order?

We supply 2-Hydroxy-thiobenzamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy-thiobenzamide?

Yes. Every lot of 2-Hydroxy-thiobenzamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy-thiobenzamide be shipped internationally?

Yes. 2-Hydroxy-thiobenzamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.