Ivermectin B1a

Name: Ivermectin B1a
Brand: Vaqora Chemicals
SKU: VQ-026274

About Ivermectin B1a

Vaqora Chemicals supplies Ivermectin B1a, a metabolite or degradation product of Ivermectin registered under CAS number 71827-03-7. Its molecular formula is C48H74O14 and its molecular weight is 875.1 g/mol. Common synonyms include Ivermectin H2B1a and Ivermectin 2-Epimer.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ivermectin, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Ivermectin B1a in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ivermectin

View every impurity, metabolite and intermediate we list for Ivermectin.

Ivermectin impurities

Specifications & identifiers

Chemical identifiers
Product name	Ivermectin B1a
Catalogue No.	VQ-026274
CAS Number	71827-03-7
IUPAC name	(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
Molecular formula	C₄₈H₇₄O₁₄
Molecular weight	875.1 g/mol
Exact mass	874.5079
Grade	Reference Standard
HSN code	38229090
InChIKey	AZSNMRSAGSSBNP-XPNPUAGNSA-N
SMILES	CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C
PubChem CID	6321424

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	3 / 14
TPSA	170 Å²
Synonyms	Ivermectin H2B1a, Ivermectin 2-Epimer, Dihydroavermectin B1a, 22,23-Dihydroavermectin B1a, avermectin H2B1a, 5-O-demethyl-22,23-dihydroavermectin A1a, H2B1a, Avermectin A1a, 5-O-demethyl-22,23-dihydro-, Ivermectin (IVM), dihydro avermectin Bla, Ivermectin (MK-0933), Ivermectin - Bio-X trade mark

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H312Harmful in contact with skin
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P302 + P352, P317, P318, P319, P321, P330, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ivermectin B1a?

The CAS Registry Number of Ivermectin B1a is 71827-03-7. It is also known as Ivermectin H2B1a, Ivermectin 2-Epimer, Dihydroavermectin B1a.

What is the molecular formula and molecular weight of Ivermectin B1a?

Ivermectin B1a has the molecular formula C48H74O14 and a molecular weight of 875.1 g/mol.

What is Ivermectin B1a used for?

Ivermectin B1a is supplied as a characterised reference material related to Ivermectin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ivermectin B1a can I order?

We supply Ivermectin B1a in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ivermectin B1a?

Yes. Every lot of Ivermectin B1a is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ivermectin B1a be shipped internationally?

Yes. Ivermectin B1a is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.