N-Boc-L-glutamic Acid alpha-Methyl Ester

Name: N-Boc-L-glutamic Acid alpha-Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-013624

About N-Boc-L-glutamic Acid alpha-Methyl Ester

N-Boc-L-glutamic Acid alpha-Methyl Ester (CAS 72086-72-7) is a process intermediate or related compound of Glutamic Acid offered by Vaqora Chemicals. Its molecular formula is C11H19NO6 and its molecular weight is 261.27 g/mol. Systematically, it is named (4S)-5-methoxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid. Common synonyms include Boc - Glu -OMe and Boc-L-glutamic acid a-methyl ester.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Glutamic Acid, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Boc-L-glutamic Acid alpha-Methyl Ester is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Glutamic Acid

View every impurity, metabolite and intermediate we list for Glutamic Acid.

Glutamic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Boc-L-glutamic Acid alpha-Methyl Ester
Catalogue No.	VQ-013624
CAS Number	72086-72-7
IUPAC name	(4S)-5-methoxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid
Molecular formula	C₁₁H₁₉NO₆
Molecular weight	261.27 g/mol
Exact mass	261.1212
Grade	Reference Standard
InChIKey	ZAYAFKXUQMTLPL-ZETCQYMHSA-N
SMILES	CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OC
PubChem CID	7018754

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 6
TPSA	102 Å²
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-L-glutamic Acid 1-Methyl Ester, N-(tert-Butoxycarbonyl)glutamic acid α-methyl ester, (S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid, Boc - Glu -OMe, (4S)-4-{[(tert-butoxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid, (4S)-4-(((tert-butoxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid, Boc-L-glutamic acid a-methyl ester, BocNH-Glu-OMe, (4S)-4-(tert-butoxycarbonylamino)-5-methoxy-5-oxo-pentanoic acid, (S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoicacid, Boc-L-Glu-Ome, (S)-4-((tert-Butoxy(hydroxy)methylene)amino)-5-methoxy-5-oxopentanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Boc-L-glutamic Acid alpha-Methyl Ester?

The CAS Registry Number of N-Boc-L-glutamic Acid alpha-Methyl Ester is 72086-72-7. It is also known as N-[(1,1-Dimethylethoxy)carbonyl]-L-glutamic Acid 1-Methyl Ester, N-(tert-Butoxycarbonyl)glutamic acid α-methyl ester, (S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid.

What is the molecular formula and molecular weight of N-Boc-L-glutamic Acid alpha-Methyl Ester?

N-Boc-L-glutamic Acid alpha-Methyl Ester has the molecular formula C11H19NO6 and a molecular weight of 261.27 g/mol. Its IUPAC name is (4S)-5-methoxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid.

What is N-Boc-L-glutamic Acid alpha-Methyl Ester used for?

N-Boc-L-glutamic Acid alpha-Methyl Ester is supplied as a characterised reference material related to Glutamic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Boc-L-glutamic Acid alpha-Methyl Ester can I order?

We supply N-Boc-L-glutamic Acid alpha-Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Boc-L-glutamic Acid alpha-Methyl Ester?

Yes. Every lot of N-Boc-L-glutamic Acid alpha-Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Boc-L-glutamic Acid alpha-Methyl Ester be shipped internationally?

Yes. N-Boc-L-glutamic Acid alpha-Methyl Ester is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.