4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane 73344-75-9

About 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane

4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane is an impurity of Ivabradine carrying the CAS registry number 73344-75-9. Formula C11H15NO2, molecular weight 193.24 g/mol. Systematically, it is named (3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methanamine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Ivabradine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivabradine

View every impurity, metabolite and intermediate we list for Ivabradine.

Ivabradine impurities

Specifications & identifiers

Chemical identifiers
Product name	4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane
Catalogue No.	VQ-037776
CAS Number	73344-75-9
IUPAC name	(3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methanamine
Molecular formula	C₁₁H₁₅NO₂
Molecular weight	193.24 g/mol
Exact mass	193.1103
Grade	Reference Standard
HSN code	38229090
InChIKey	JDZSBHBIJDIACW-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(CC2=C1)CN)OC
PubChem CID	423512

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 3
TPSA	44.5 Å²
Synonyms	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine, (3,4-Dimethoxy-bicyclo(4.2.0)octa-1,3,5-trien-7-yl)-methylamine, (3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine, (4,5-Dimethoxy-1,2-dihydrocyclobutabenzen-1-yl)methanamine, (3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methanamine, 1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine, Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3,4-dimethoxy-, c-(3,4-dimethoxy-bicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)-methylamine, {3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl}methanamine, 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane hydrochloride

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane?

The CAS Registry Number of 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane is 73344-75-9. It is also known as (3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine, (3,4-Dimethoxy-bicyclo(4.2.0)octa-1,3,5-trien-7-yl)-methylamine, (3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine.

What is the molecular formula and molecular weight of 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane?

4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane has the molecular formula C11H15NO2 and a molecular weight of 193.24 g/mol. Its IUPAC name is (3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methanamine.

What is 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane used for?

4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane is supplied as a characterised reference material related to Ivabradine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane can I order?

We supply 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane?

Yes. Every lot of 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane be shipped internationally?

Yes. We export 4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.