O-Desmethyl Astemizole

Name: O-Desmethyl Astemizole
Brand: Vaqora Chemicals
SKU: VQ-021631

About O-Desmethyl Astemizole

O-Desmethyl Astemizole (CAS 73736-50-2) is a metabolite or degradation product of Astemizole offered by Vaqora Chemicals. Formula C27H29FN4O, molecular weight 444.5 g/mol. Its systematic (IUPAC) name is 4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenol. Common synonyms include O-Demethylastemizole.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Astemizole, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer O-Desmethyl Astemizole in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Astemizole

View every impurity, metabolite and intermediate we list for Astemizole.

Astemizole impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Astemizole
Catalogue No.	VQ-021631
CAS Number	73736-50-2
IUPAC name	4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenol
Molecular formula	C₂₇H₂₉FN₄O
Molecular weight	444.5 g/mol
Exact mass	444.2325
Grade	Reference Standard
HSN code	38229090
InChIKey	LAGYWHSFHIMTPE-UHFFFAOYSA-N
SMILES	C1CN(CCC1NC2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)CCC5=CC=C(C=C5)O
PubChem CID	155805

Physical properties
Physical form	Solid
LogP (XLogP3)	5.6
H-bond donors / acceptors	2 / 5
TPSA	53.3 Å²
Synonyms	4-(2-(4-((1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)piperidin-1-yl)ethyl)phenol, O-Demethylastemizole, 4-(2-(4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-ylamino)piperidin-1-yl)ethyl)phenol, 4-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-ylamino]-piperidin-1-yl}-ethyl)-phenol, 4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]-1-piperidyl]ethyl]phenol, 4-[2-[4-[[1-[(4-luorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenol, 4-[2-{4-[1-(4-fluorophenylmethyl)-1H-benzimidazol-2-ylamino]-1-piperidinyl}ethyl]phenol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Astemizole?

The CAS Registry Number of O-Desmethyl Astemizole is 73736-50-2. It is also known as 4-(2-(4-((1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)piperidin-1-yl)ethyl)phenol, O-Demethylastemizole, 4-(2-(4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-ylamino)piperidin-1-yl)ethyl)phenol.

What is the molecular formula and molecular weight of O-Desmethyl Astemizole?

O-Desmethyl Astemizole has the molecular formula C27H29FN4O and a molecular weight of 444.5 g/mol. Its IUPAC name is 4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenol.

What is O-Desmethyl Astemizole used for?

O-Desmethyl Astemizole is supplied as a characterised reference material related to Astemizole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Astemizole can I order?

We supply O-Desmethyl Astemizole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Astemizole?

Yes. Every lot of O-Desmethyl Astemizole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Astemizole be shipped internationally?

Yes. We export O-Desmethyl Astemizole worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.