Edoxaban M8

About Edoxaban M8

Edoxaban M8 is a metabolite or degradation product of Edoxaban carrying the CAS registry number 740794-83-6. The compound has the formula C23H28ClN7O4S, corresponding to a molecular weight of 534.0 g/mol. Alternative names: Edoxaban (SRS)-Isomer and N-Monomethyl edoxaban.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Edoxaban, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Edoxaban

View every impurity, metabolite and intermediate we list for Edoxaban.

Edoxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Edoxaban M8
Catalogue No.	VQ-025470
CAS Number	740794-83-6
IUPAC name	N'-(5-chloro-2-pyridinyl)-N-[(1S,2R,4S)-4-(methylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide
Molecular formula	C₂₃H₂₈ClN₇O₄S
Molecular weight	534 g/mol
Exact mass	533.1612
Grade	Reference Standard
HSN code	38229090
InChIKey	XEESEADVQCJXSF-DUVNUKRYSA-N
SMILES	CNC(=O)[C@H]1CC[C@@H]([C@@H](C1)NC(=O)C2=NC3=C(S2)CN(CC3)C)NC(=O)C(=O)NC4=NC=C(C=C4)Cl
PubChem CID	59676785

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	4 / 8
TPSA	174 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Edoxaban M8?

The CAS Registry Number of Edoxaban M8 is 740794-83-6. It is also known as Edoxaban (SRS)-Isomer, N-Monomethyl edoxaban, Edoxaban metabolite M8.

What is the molecular formula and molecular weight of Edoxaban M8?

Edoxaban M8 has the molecular formula C23H28ClN7O4S and a molecular weight of 534 g/mol. Its IUPAC name is N'-(5-chloro-2-pyridinyl)-N-[(1S,2R,4S)-4-(methylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide.

What is Edoxaban M8 used for?

Edoxaban M8 is supplied as a characterised reference material related to Edoxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Edoxaban M8 can I order?

We supply Edoxaban M8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Edoxaban M8?

Yes. Every lot of Edoxaban M8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Edoxaban M8 be shipped internationally?

Yes. We export Edoxaban M8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.