4-Hydroxy Duloxetine β-D-Glucuronide

Name: 4-Hydroxy Duloxetine β-D-Glucuronide
Brand: Vaqora Chemicals
SKU: VQ-030334

About 4-Hydroxy Duloxetine β-D-Glucuronide

Listed under CAS 741693-83-4, 4-Hydroxy Duloxetine β-D-Glucuronide is a metabolite or degradation product of Duloxetine available from Vaqora Chemicals. With the molecular formula C24H27NO8S, it has a molar mass of 489.5 g/mol. It is also known as Duloxetine 4-hydroxyglucuronide or 4-Hydroxy Duloxetine beta-D-Glucuronide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Duloxetine, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Hydroxy Duloxetine β-D-Glucuronide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Duloxetine β-D-Glucuronide
Catalogue No.	VQ-030334
CAS Number	741693-83-4
IUPAC name	(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-yl]oxyoxane-2-carboxylic acid
Molecular formula	C₂₄H₂₇NO₈S
Molecular weight	489.5 g/mol
Exact mass	489.1457
Grade	Reference Standard
HSN code	38229090
InChIKey	OBIZFSZXDHWUJZ-ANUWOGMRSA-N
SMILES	CNCC[C@@H](C1=CC=CS1)OC2=CC=C(C3=CC=CC=C32)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O
PubChem CID	29981513

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	5 / 10
TPSA	166 Å²
Synonyms	Duloxetine 4-hydroxyglucuronide, 4-Hydroxy Duloxetine beta-D-Glucuronide, 4-Hydroxy Duloxetine b-D-Glucuronide, 4-Hydroxy duloxetine glucuronide, 4-Hydroxyduloxetine-glucuronide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Duloxetine β-D-Glucuronide?

The CAS Registry Number of 4-Hydroxy Duloxetine β-D-Glucuronide is 741693-83-4. It is also known as Duloxetine 4-hydroxyglucuronide, 4-Hydroxy Duloxetine beta-D-Glucuronide, 4-Hydroxy Duloxetine b-D-Glucuronide.

What is the molecular formula and molecular weight of 4-Hydroxy Duloxetine β-D-Glucuronide?

4-Hydroxy Duloxetine β-D-Glucuronide has the molecular formula C24H27NO8S and a molecular weight of 489.5 g/mol. Its IUPAC name is (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-yl]oxyoxane-2-carboxylic acid.

What is 4-Hydroxy Duloxetine β-D-Glucuronide used for?

4-Hydroxy Duloxetine β-D-Glucuronide is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Duloxetine β-D-Glucuronide can I order?

We supply 4-Hydroxy Duloxetine β-D-Glucuronide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Duloxetine β-D-Glucuronide?

Yes. Every lot of 4-Hydroxy Duloxetine β-D-Glucuronide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Duloxetine β-D-Glucuronide be shipped internationally?

Yes. We export 4-Hydroxy Duloxetine β-D-Glucuronide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.