Argatroban

About Argatroban

Argatroban is a high-purity reference standard of Argatroban carrying the CAS registry number 74863-84-6. The compound has the formula C23H36N6O5S, corresponding to a molecular weight of 508.6 g/mol. It is also known as Argatroban Monohydrate or Argatroban anhydrous.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Argatroban, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Argatroban

View every impurity, metabolite and intermediate we list for Argatroban.

Argatroban impurities

Specifications & identifiers

Chemical identifiers
Product name	Argatroban
Catalogue No.	VQ-024354
CAS Number	74863-84-6
IUPAC name	(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
Molecular formula	C₂₃H₃₆N₆O₅S
Molecular weight	508.6 g/mol
Exact mass	508.2468
Grade	Reference Standard
HSN code	38229090
InChIKey	KXNPVXPOPUZYGB-IOVMHBDKSA-N
SMILES	C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C
PubChem CID	92722

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	5 / 8
TPSA	189 Å²
Synonyms	Argatroban Monohydrate, Argatroban anhydrous, Argipidine, MD-805, MCI-9038, Argatroban In Sodium Chloride, Argatrobanum (Latin), Argatroban Injection, 74863-84-6 (anhydrous), EX-A4276

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Argatroban?

The CAS Registry Number of Argatroban is 74863-84-6. It is also known as Argatroban Monohydrate, Argatroban anhydrous, Argipidine.

What is the molecular formula and molecular weight of Argatroban?

Argatroban has the molecular formula C23H36N6O5S and a molecular weight of 508.6 g/mol. Its IUPAC name is (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid.

What is Argatroban used for?

Argatroban is supplied as a characterised reference material related to Argatroban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Argatroban can I order?

We supply Argatroban in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Argatroban?

Yes. Every lot of Argatroban is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Argatroban be shipped internationally?

Yes. Argatroban is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.