(R,R)-Diltiazem

About (R,R)-Diltiazem

(R,R)-Diltiazem is a high-purity reference standard of Diltiazem carrying the CAS registry number 75472-92-3. Its molecular formula is C22H26N2O4S and its molecular weight is 414.5 g/mol. Its systematic (IUPAC) name is [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. It is also known as d-cis-Diltiazem or Dilcontin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Diltiazem standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,R)-Diltiazem
Catalogue No.	VQ-044664
CAS Number	75472-92-3
IUPAC name	[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
Molecular formula	C₂₂H₂₆N₂O₄S
Molecular weight	414.5 g/mol
Exact mass	414.1613
Grade	Reference Standard
HSN code	38229090
InChIKey	HSUGRBWQSSZJOP-RTWAWAEBSA-N
SMILES	CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
PubChem CID	39186

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 6
TPSA	84.4 Å²
Synonyms	(R,R)-Diltiazem, (-)-cis-Diltiazem, (-)-Diltiazem, d-cis-Diltiazem, Dilcontin, Anoheal, Incoril AP, Dilacor-XR, Diltiazem extended release, Diltia XT, (+)-diltiazem, (+)-cis-diltiazem, Dilt-cd

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,R)-Diltiazem?

The CAS Registry Number of (R,R)-Diltiazem is 75472-92-3. It is also known as (R,R)-Diltiazem, (-)-cis-Diltiazem, (-)-Diltiazem, d-cis-Diltiazem, Dilcontin.

What is the molecular formula and molecular weight of (R,R)-Diltiazem?

(R,R)-Diltiazem has the molecular formula C22H26N2O4S and a molecular weight of 414.5 g/mol. Its IUPAC name is [(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate.

What is (R,R)-Diltiazem used for?

(R,R)-Diltiazem is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,R)-Diltiazem can I order?

We supply (R,R)-Diltiazem in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,R)-Diltiazem?

Yes. Every lot of (R,R)-Diltiazem is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,R)-Diltiazem be shipped internationally?

Yes. We export (R,R)-Diltiazem worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.