2-Bromo-N-Isopropylacetamide

About 2-Bromo-N-Isopropylacetamide

2-Bromo-N-Isopropylacetamide is a process intermediate or related compound of Belumosudil carrying the CAS registry number 75726-96-4. Its molecular formula is C5H10BrNO and its molecular weight is 180.04 g/mol. Its systematic (IUPAC) name is 2-bromo-N-propan-2-ylacetamide. Common synonyms include 2-bromo-N-(propan-2-yl)acetamide and Acetamide, 2-bromo-N-(1-methylethyl)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Belumosudil, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Bromo-N-Isopropylacetamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Belumosudil

View every impurity, metabolite and intermediate we list for Belumosudil.

Belumosudil impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Bromo-N-Isopropylacetamide
Catalogue No.	VQ-051979
CAS Number	75726-96-4
IUPAC name	2-bromo-N-propan-2-ylacetamide
Molecular formula	C₅H₁₀BrNO
Molecular weight	180.04 g/mol
Exact mass	178.9946
InChIKey	ZLDCRYWMEQJDGW-UHFFFAOYSA-N
SMILES	CC(C)NC(=O)CBr
PubChem CID	12509261

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	2-bromo-N-(propan-2-yl)acetamide, Acetamide, 2-bromo-N-(1-methylethyl)-, 2-bromo-n-(1-methylethyl)acetamide, 2-bromo-N-(methylethyl)acetamide, N-isopropylbromoacetamide, N-Isopropyl-2-bromoacetamide, N-(Bromoacetyl)isopropylamine, 2Bromo-N-(propan-2-yl)acetamide

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Bromo-N-Isopropylacetamide?

The CAS Registry Number of 2-Bromo-N-Isopropylacetamide is 75726-96-4. It is also known as 2-bromo-N-(propan-2-yl)acetamide, Acetamide, 2-bromo-N-(1-methylethyl)-, 2-bromo-n-(1-methylethyl)acetamide.

What is the molecular formula and molecular weight of 2-Bromo-N-Isopropylacetamide?

2-Bromo-N-Isopropylacetamide has the molecular formula C5H10BrNO and a molecular weight of 180.04 g/mol. Its IUPAC name is 2-bromo-N-propan-2-ylacetamide.

What is 2-Bromo-N-Isopropylacetamide used for?

2-Bromo-N-Isopropylacetamide is supplied as a characterised reference material related to Belumosudil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Bromo-N-Isopropylacetamide can I order?

We supply 2-Bromo-N-Isopropylacetamide, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Bromo-N-Isopropylacetamide?

Yes. Every lot of 2-Bromo-N-Isopropylacetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Bromo-N-Isopropylacetamide be shipped internationally?

Yes. 2-Bromo-N-Isopropylacetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.