3-Ethyl-4-methyl-2-oxopyrroline

About 3-Ethyl-4-methyl-2-oxopyrroline

3-Ethyl-4-methyl-2-oxopyrroline is a high-purity reference standard of Glimepiride carrying the CAS registry number 766-36-9. The compound has the formula C7H11NO, corresponding to a molecular weight of 125.17 g/mol. The IUPAC name is 4-ethyl-3-methyl-1,2-dihydropyrrol-5-one. It is also known as 3-Ethyl-4-methyl-3-pyrrolin-2-one or 3-Ethyl-4-methyl-3-pyrolline-2-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Glimepiride, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 3-Ethyl-4-methyl-2-oxopyrroline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material
Fine chemical synthesis

Industries

Related to Glimepiride

View every impurity, metabolite and intermediate we list for Glimepiride.

Glimepiride impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Ethyl-4-methyl-2-oxopyrroline
Catalogue No.	VQ-037473
CAS Number	766-36-9
IUPAC name	4-ethyl-3-methyl-1,2-dihydropyrrol-5-one
Molecular formula	C₇H₁₁NO
Molecular weight	125.17 g/mol
Exact mass	125.0841
Grade	Reference Standard
HSN code	38229090
InChIKey	YCTNTSVMJWIYTQ-UHFFFAOYSA-N
SMILES	CCC1=C(CNC1=O)C
PubChem CID	854146

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	3-Ethyl-4-methyl-3-pyrrolin-2-one, 3-Ethyl-4-methyl-3-pyrolline-2-one, 3-Ethyl-4-methyl-2,5-dihydro-1H-pyrrol-2-one, 3-Ethyl-4-methyl-3-pyrroline-2-one, 2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-4-methyl-, 3-ethyl-4-methylpyrroline-2-one, 3-Pyrrolin-2-one, 3-ethyl-4-methyl-

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Ethyl-4-methyl-2-oxopyrroline?

The CAS Registry Number of 3-Ethyl-4-methyl-2-oxopyrroline is 766-36-9. It is also known as 3-Ethyl-4-methyl-3-pyrrolin-2-one, 3-Ethyl-4-methyl-3-pyrolline-2-one, 3-Ethyl-4-methyl-2,5-dihydro-1H-pyrrol-2-one.

What is the molecular formula and molecular weight of 3-Ethyl-4-methyl-2-oxopyrroline?

3-Ethyl-4-methyl-2-oxopyrroline has the molecular formula C7H11NO and a molecular weight of 125.17 g/mol. Its IUPAC name is 4-ethyl-3-methyl-1,2-dihydropyrrol-5-one.

What is 3-Ethyl-4-methyl-2-oxopyrroline used for?

3-Ethyl-4-methyl-2-oxopyrroline is supplied as a characterised reference material related to Glimepiride. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Ethyl-4-methyl-2-oxopyrroline can I order?

We supply 3-Ethyl-4-methyl-2-oxopyrroline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Ethyl-4-methyl-2-oxopyrroline?

Yes. Every lot of 3-Ethyl-4-methyl-2-oxopyrroline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Ethyl-4-methyl-2-oxopyrroline be shipped internationally?

Yes. 3-Ethyl-4-methyl-2-oxopyrroline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.