Dabigatran Methyl Ester

About Dabigatran Methyl Ester

Dabigatran Methyl Ester is a process intermediate or related compound of Dabigatran carrying the CAS registry number 771459-37-1. Formula C26H27N7O3, molecular weight 485.5 g/mol. The IUPAC name is methyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate. Common synonyms include Dabigatran methyl Ester Amidine and Dabigatran metabolite M486-2.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Dabigatran, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dabigatran Methyl Ester is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dabigatran

View every impurity, metabolite and intermediate we list for Dabigatran.

Dabigatran impurities

Specifications & identifiers

Chemical identifiers
Product name	Dabigatran Methyl Ester
Catalogue No.	VQ-013330
CAS Number	771459-37-1
Other CAS	211914-58-8
IUPAC name	methyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate
Molecular formula	C₂₆H₂₇N₇O₃
Molecular weight	485.5 g/mol
Exact mass	485.2175
Grade	Reference Standard
HSN code	2933
InChIKey	YNXUXWCCKIZGCU-UHFFFAOYSA-N
SMILES	CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)OC)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
PubChem CID	18412517

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 7
TPSA	139 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dabigatran Methyl Ester?

The CAS Registry Number of Dabigatran Methyl Ester is 771459-37-1. It is also known as Dabigatran methyl Ester Amidine, Dabigatran metabolite M486-2.

What is the molecular formula and molecular weight of Dabigatran Methyl Ester?

Dabigatran Methyl Ester has the molecular formula C26H27N7O3 and a molecular weight of 485.5 g/mol. Its IUPAC name is methyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate.

What is Dabigatran Methyl Ester used for?

Dabigatran Methyl Ester is supplied as a characterised reference material related to Dabigatran. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dabigatran Methyl Ester can I order?

We supply Dabigatran Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dabigatran Methyl Ester?

Yes. Every lot of Dabigatran Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dabigatran Methyl Ester be shipped internationally?

Yes. We export Dabigatran Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.