3-(Trifluoromethyl)cinnamic Acid

About 3-(Trifluoromethyl)cinnamic Acid

3-(Trifluoromethyl)cinnamic Acid is an impurity of Cinnamic Acid carrying the CAS registry number 779-89-5. Its molecular formula is C10H7F3O2 and its molecular weight is 216.16 g/mol. Its systematic (IUPAC) name is (E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid. Common synonyms include (E)-m-(Trifluoromethyl)cinnamic acid and m-(trifluoromethyl)cinnamic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Cinnamic Acid impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cinnamic Acid

View every impurity, metabolite and intermediate we list for Cinnamic Acid.

Cinnamic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(Trifluoromethyl)cinnamic Acid
Catalogue No.	VQ-032386
CAS Number	779-89-5
IUPAC name	(E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid
Molecular formula	C₁₀H₇F₃O₂
Molecular weight	216.16 g/mol
Exact mass	216.0398
Grade	Reference Standard
HSN code	38229090
InChIKey	KSBWHDDGWSYETA-SNAWJCMRSA-N
SMILES	C1=CC(=CC(=C1)C(F)(F)F)/C=C/C(=O)O
PubChem CID	719451

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	1 / 5
TPSA	37.3 Å²
Synonyms	(E)-m-(Trifluoromethyl)cinnamic acid, m-(trifluoromethyl)cinnamic acid, 3-(3-(Trifluoromethyl)phenyl)acrylic acid, trans-3-(trifluoromethyl)cinnamic acid, 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, (2E)-, 2-Propenoic acid, 3-(3-(trifluoromethyl)phenyl)-, (2E)-3-[3-(Trifluoromethyl)phenyl]-2-propenoic acid, m-(Trifluoromethyl)cinnamic acid, (trans)-, 2-Propenoic acid, 3-(3-(trifluoromethyl)phenyl)-, (2E)-, 3-(3-(Trifluoromethyl)phenyl)-2-propenoic acid, 3-[3-(trifluoromethyl)phenyl]acrylic acid, 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(Trifluoromethyl)cinnamic Acid?

The CAS Registry Number of 3-(Trifluoromethyl)cinnamic Acid is 779-89-5. It is also known as (E)-m-(Trifluoromethyl)cinnamic acid, m-(trifluoromethyl)cinnamic acid, 3-(3-(Trifluoromethyl)phenyl)acrylic acid.

What is the molecular formula and molecular weight of 3-(Trifluoromethyl)cinnamic Acid?

3-(Trifluoromethyl)cinnamic Acid has the molecular formula C10H7F3O2 and a molecular weight of 216.16 g/mol. Its IUPAC name is (E)-3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid.

What is 3-(Trifluoromethyl)cinnamic Acid used for?

3-(Trifluoromethyl)cinnamic Acid is supplied as a characterised reference material related to Cinnamic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(Trifluoromethyl)cinnamic Acid can I order?

We supply 3-(Trifluoromethyl)cinnamic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(Trifluoromethyl)cinnamic Acid?

Yes. Every lot of 3-(Trifluoromethyl)cinnamic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(Trifluoromethyl)cinnamic Acid be shipped internationally?

Yes. 3-(Trifluoromethyl)cinnamic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.