3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b… 78213-40-8

Name: 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine
Brand: Vaqora Chemicals
SKU: VQ-025052

About 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine

3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine (CAS 78213-40-8) is a nitrosamine impurity of Clomipramine offered by Vaqora Chemicals. Its molecular formula is C14H11ClN2O and its molecular weight is 258.7 g/mol. Its systematic (IUPAC) name is 2-chloro-11-nitroso-5,6-dihydrobenzo[b][1]benzazepine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Clomipramine, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Clomipramine

View every impurity, metabolite and intermediate we list for Clomipramine.

Clomipramine impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine
Catalogue No.	VQ-025052
CAS Number	78213-40-8
IUPAC name	2-chloro-11-nitroso-5,6-dihydrobenzo[b][1]benzazepine
Molecular formula	C₁₄H₁₁ClN₂O
Molecular weight	258.7 g/mol
Exact mass	258.056
Grade	Reference Standard
HSN code	38229090
InChIKey	FFOWVWMBIAZDDI-UHFFFAOYSA-N
SMILES	C1CC2=CC=CC=C2N(C3=C1C=CC(=C3)Cl)N=O
PubChem CID	165429021

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	0 / 3
TPSA	32.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine?

The CAS Registry Number of 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine is 78213-40-8.

What is the molecular formula and molecular weight of 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine?

3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine has the molecular formula C14H11ClN2O and a molecular weight of 258.7 g/mol. Its IUPAC name is 2-chloro-11-nitroso-5,6-dihydrobenzo[b][1]benzazepine.

What is 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine used for?

3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine is supplied as a characterised reference material related to Clomipramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine can I order?

We supply 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine?

Yes. Every lot of 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine be shipped internationally?

Yes. We export 3-Chloro-5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.