Diethyl 2-(4-amino-3-fluorophenyl)-2-methylma… 78543-08-5

About Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate

Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate is an impurity of Flurbiprofen carrying the CAS registry number 78543-08-5. The compound has the formula C14H18FNO4, corresponding to a molecular weight of 283.29 g/mol. The IUPAC name is diethyl 2-(4-amino-3-fluorophenyl)-2-methylpropanedioate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Flurbiprofen impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Flurbiprofen

View every impurity, metabolite and intermediate we list for Flurbiprofen.

Flurbiprofen impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate
Catalogue No.	VQ-037368
CAS Number	78543-08-5
IUPAC name	diethyl 2-(4-amino-3-fluorophenyl)-2-methylpropanedioate
Molecular formula	C₁₄H₁₈FNO₄
Molecular weight	283.29 g/mol
Exact mass	283.122
Grade	Reference Standard
HSN code	38229090
InChIKey	AXSSLCGWLSGEET-UHFFFAOYSA-N
SMILES	CCOC(=O)C(C)(C1=CC(=C(C=C1)N)F)C(=O)OCC
PubChem CID	11630571

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 6
TPSA	78.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate?

The CAS Registry Number of Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate is 78543-08-5. It is also known as Diethyl (4-amino-3-fluorophenyl)methylmalonate, 1,3-diethyl 2-(4-amino-3-fluorophenyl)-2-methylpropanedioate, diethyl(4-amino-3-fluorophenyl)(methyl)propanedioate.

What is the molecular formula and molecular weight of Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate?

Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate has the molecular formula C14H18FNO4 and a molecular weight of 283.29 g/mol. Its IUPAC name is diethyl 2-(4-amino-3-fluorophenyl)-2-methylpropanedioate.

What is Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate used for?

Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate is supplied as a characterised reference material related to Flurbiprofen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate can I order?

We supply Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate?

Yes. Every lot of Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate be shipped internationally?

Yes. We export Diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.