Iloprost

About Iloprost

Iloprost is a high-purity reference standard of Iloprost carrying the CAS registry number 78919-13-8. Formula C22H32O4, molecular weight 360.5 g/mol. Common synonyms include Ilomedin and Iloprost Clathrate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Iloprost standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Iloprost

View every impurity, metabolite and intermediate we list for Iloprost.

Iloprost impurities

Specifications & identifiers

Chemical identifiers
Product name	Iloprost
Catalogue No.	VQ-031165
CAS Number	78919-13-8
IUPAC name	(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
Molecular formula	C₂₂H₃₂O₄
Molecular weight	360.5 g/mol
Exact mass	360.2301
Grade	Reference Standard
HSN code	38229090
InChIKey	HIFJCPQKFCZDDL-ACWOEMLNSA-N
SMILES	CC#CCC(C)[C@@H](/C=C/[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/C2)O)O
PubChem CID	5311181

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	3 / 4
TPSA	77.8 Å²
Synonyms	Ilomedin, Iloprost Clathrate, 5-cis Iloprost, [3H]-Iloprost, (16R,S)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I2, Ilomedine, EX-A6213, SH-401, BAY Q6256, BAY-q-6256, (16R,S)-Methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I(sub 2)

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P318, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Iloprost?

The CAS Registry Number of Iloprost is 78919-13-8. It is also known as Ilomedin, Iloprost Clathrate, 5-cis Iloprost.

What is the molecular formula and molecular weight of Iloprost?

Iloprost has the molecular formula C22H32O4 and a molecular weight of 360.5 g/mol. Its IUPAC name is (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid.

What is Iloprost used for?

Iloprost is supplied as a characterised reference material related to Iloprost. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Iloprost can I order?

We supply Iloprost in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Iloprost?

Yes. Every lot of Iloprost is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Iloprost be shipped internationally?

Yes. Iloprost is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.