Clofedanol

Name: Clofedanol
Brand: Vaqora Chemicals
SKU: VQ-029867

About Clofedanol

Clofedanol is an API impurity reference standard carrying the CAS registry number 791-35-5. The compound has the formula C17H20ClNO, corresponding to a molecular weight of 289.8 g/mol. The IUPAC name is 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol. It is also known as Chlophedianol or Chlofedanol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Clofedanol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Clofedanol
Catalogue No.	VQ-029867
CAS Number	791-35-5
IUPAC name	1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol
Molecular formula	C₁₇H₂₀ClNO
Molecular weight	289.8 g/mol
Exact mass	289.1233
Grade	Reference Standard
HSN code	38229090
InChIKey	WRCHFMBCVFFYEQ-UHFFFAOYSA-N
SMILES	CN(C)CCC(C1=CC=CC=C1)(C2=CC=CC=C2Cl)O
PubChem CID	2795

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 2
TPSA	23.5 Å²
Synonyms	Chlophedianol, Chlofedanol, Clophedianol base, Antitussin, 1-Phenyl-1-(o-chlorophenyl)-3-dimethylaminopropanol, alpha-(Dimethylaminoethyl)-o-chlorobenzhydrol, 2-Chloro-alpha-(2-(dimethylamino)ethyl)benzhydrol, chlophendianol hydrochloride, 2-Chloro-alpha-(2-dimethylaminoethyl)benzhydrol, Dencyl, Calmotusin, Ulo base

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clofedanol?

The CAS Registry Number of Clofedanol is 791-35-5. It is also known as Chlophedianol, Chlofedanol, Clophedianol base.

What is the molecular formula and molecular weight of Clofedanol?

Clofedanol has the molecular formula C17H20ClNO and a molecular weight of 289.8 g/mol. Its IUPAC name is 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol.

Which grade and pack sizes of Clofedanol can I order?

We supply Clofedanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clofedanol?

Yes. Every lot of Clofedanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clofedanol be shipped internationally?

Yes. Clofedanol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.