N-Desethyl Amodiaquine

Name: N-Desethyl Amodiaquine
Brand: Vaqora Chemicals
SKU: VQ-020665

About N-Desethyl Amodiaquine

N-Desethyl Amodiaquine is a metabolite or degradation product of Amodiaquine carrying the CAS registry number 79352-78-6. Its molecular formula is C18H18ClN3O and its molecular weight is 327.8 g/mol. Systematically, it is named 4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol. Alternative names: Desethylamodiaquine and Monodesethylamodiaquine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Amodiaquine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Desethyl Amodiaquine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Amodiaquine

View every impurity, metabolite and intermediate we list for Amodiaquine.

Amodiaquine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desethyl Amodiaquine
Catalogue No.	VQ-020665
CAS Number	79352-78-6
IUPAC name	4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol
Molecular formula	C₁₈H₁₈ClN₃O
Molecular weight	327.8 g/mol
Exact mass	327.1138
Grade	Reference Standard
HSN code	38229090
InChIKey	VRXFDHAGFYWGHT-UHFFFAOYSA-N
SMILES	CCNCC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O
PubChem CID	122068

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	3 / 4
TPSA	57.2 Å²
Synonyms	Desethylamodiaquine, Monodesethylamodiaquine, 4-((7-Chloro-4-quinolinyl)amino)-2-((ethylamino)methyl)phenol, Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((ethylamino)methyl)-, N-Desethyl amodiaquine diHCl, 4-((7-Chloroquinolin-4-yl)amino)-2-((ethylamino)methyl)phenol, 4-[(7-chloroquinolin-4-yl)amino]-2-[(ethylamino)methyl]phenol, 4-[(7-chloro-4-quinolyl)amino]-2-(ethylaminomethyl)phenol, bidesethylamodiaquine, Des-ethylamodiaquine, (Discontinued see D288826)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desethyl Amodiaquine?

The CAS Registry Number of N-Desethyl Amodiaquine is 79352-78-6. It is also known as Desethylamodiaquine, Monodesethylamodiaquine, 4-((7-Chloro-4-quinolinyl)amino)-2-((ethylamino)methyl)phenol.

What is the molecular formula and molecular weight of N-Desethyl Amodiaquine?

N-Desethyl Amodiaquine has the molecular formula C18H18ClN3O and a molecular weight of 327.8 g/mol. Its IUPAC name is 4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol.

What is N-Desethyl Amodiaquine used for?

N-Desethyl Amodiaquine is supplied as a characterised reference material related to Amodiaquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desethyl Amodiaquine can I order?

We supply N-Desethyl Amodiaquine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desethyl Amodiaquine?

Yes. Every lot of N-Desethyl Amodiaquine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desethyl Amodiaquine be shipped internationally?

Yes. N-Desethyl Amodiaquine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.