Maytansinoid DM 4
Synonyms: Ravtansine · N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine · N2'-(4-((3-carboxypropyl)dithio)-4-methyl-1-oxo-2-sulfopentyl)-N2'-deacetylmaytansine · N2'-[4-[(3-carboxypropyl)dithio]-4-methyl-1-oxo-2-sulfopentyl]-N2'-deacetylmaytansine
Maytansinoid DM 4 (CAS 796073-69-3) – Mertansine impurity standard. C38H54ClN3O10S, MW 780.4. COA included. Worldwide shipping from Vaqora Chemicals.
About Maytansinoid DM 4
Maytansinoid DM 4 (CAS 796073-69-3) is an impurity of Mertansine offered by Vaqora Chemicals. Formula C38H54ClN3O10S, molecular weight 780.4 g/mol. It is also known as Ravtansine or DM 4.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.
Pharmaceutical QC and development laboratories use this impurity standard of Mertansine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Mertansine.
Mertansine impuritiesSpecifications & identifiers
| Product name | Maytansinoid DM 4 |
|---|---|
| Catalogue No. | VQ-038314 |
| CAS Number | 796073-69-3 |
| IUPAC name | [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl-(4-methyl-4-sulfanylpentanoyl)amino]propanoate |
| Molecular formula | C38H54ClN3O10S |
| Molecular weight | 780.4 g/mol |
| Exact mass | 779.3218 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | JFCFGYGEYRIEBE-YVLHJLIDSA-N |
| SMILES | C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)S)C)\C)OC)(NC(=O)O2)O |
| PubChem CID | 11686439 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.2 |
| H-bond donors / acceptors | 3 / 11 |
| TPSA | 157 Ų |
| Synonyms | Ravtansine, N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine, N2'-(4-((3-carboxypropyl)dithio)-4-methyl-1-oxo-2-sulfopentyl)-N2'-deacetylmaytansine, N2'-[4-[(3-carboxypropyl)dithio]-4-methyl-1-oxo-2-sulfopentyl]-N2'-deacetylmaytansine, DM 4, DM-4, EX-A3441, Maytansine, N2a(2)-deacetyl-N2a(2)-(4-mercapto-4-methyl-1-oxopentyl)- |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H300Fatal if swallowedH301Toxic if swallowedH310Fatal in contact with skinH311Toxic in contact with skinH314Causes severe skin burns and eye damageH315Causes skin irritationH319Causes serious eye irritationH331Toxic if inhaledH340May cause genetic defectsH341Suspected of causing genetic defectsH360May damage fertility or the unborn childH361Suspected of damaging fertility or the unborn childH370Causes damage to organsH373May causes damage to organs through prolonged or repeated exposure
Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P308 + P316, P316, P318, P319, P321, P330, P332 + P317, P337 + P317
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Maytansinoid DM 4?
The CAS Registry Number of Maytansinoid DM 4 is 796073-69-3. It is also known as Ravtansine, N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine, N2'-(4-((3-carboxypropyl)dithio)-4-methyl-1-oxo-2-sulfopentyl)-N2'-deacetylmaytansine.
What is the molecular formula and molecular weight of Maytansinoid DM 4?
Maytansinoid DM 4 has the molecular formula C38H54ClN3O10S and a molecular weight of 780.4 g/mol.
What is Maytansinoid DM 4 used for?
Maytansinoid DM 4 is supplied as a characterised reference material related to Mertansine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Maytansinoid DM 4 can I order?
We supply Maytansinoid DM 4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Maytansinoid DM 4?
Yes. Every lot of Maytansinoid DM 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Maytansinoid DM 4 be shipped internationally?
Yes. Maytansinoid DM 4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Maytansinoid DM 4
We reply within one business day with price, pack options, lead time and documentation.
Related products
- CAS
- 1228105-51-8
- Formula
- C51H66ClN5O16S
- MW
- 1072.6 g/mol