4-Chlorophenyl Phenyl Sulfone

About 4-Chlorophenyl Phenyl Sulfone

4-Chlorophenyl Phenyl Sulfone is an impurity of Dapsone carrying the CAS registry number 80-00-2. The compound has the formula C12H9ClO2S, corresponding to a molecular weight of 252.72 g/mol. Systematically, it is named 1-(benzenesulfonyl)-4-chlorobenzene. It is also known as Sulfenone or 1-Chloro-4-(phenylsulfonyl)benzene.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Dapsone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dapsone

View every impurity, metabolite and intermediate we list for Dapsone.

Dapsone impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chlorophenyl Phenyl Sulfone
Catalogue No.	VQ-025188
CAS Number	80-00-2
IUPAC name	1-(benzenesulfonyl)-4-chlorobenzene
Molecular formula	C₁₂H₉ClO₂S
Molecular weight	252.72 g/mol
Exact mass	252.0012
Grade	Reference Standard
HSN code	38229090
InChIKey	OFCFYWOKHPOXKF-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)Cl
PubChem CID	6621

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 2
TPSA	42.5 Å²
Synonyms	Sulfenone, 1-Chloro-4-(phenylsulfonyl)benzene, 4-Chlorodiphenyl sulfone, Benzene, 1-chloro-4-(phenylsulfonyl)-, p-Chlorophenyl phenyl sulfone, Compound R-242, p-Chlorophenyl phenyl sulphone, Sulfone, p-chlorophenyl phenyl, p-Monochlorophenyl phenyl sulfone, R-242-B, 4-Chlorodiphenyl sulphone, 4-Chlordifenylsulfon

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chlorophenyl Phenyl Sulfone?

The CAS Registry Number of 4-Chlorophenyl Phenyl Sulfone is 80-00-2. It is also known as Sulfenone, 1-Chloro-4-(phenylsulfonyl)benzene, 4-Chlorodiphenyl sulfone.

What is the molecular formula and molecular weight of 4-Chlorophenyl Phenyl Sulfone?

4-Chlorophenyl Phenyl Sulfone has the molecular formula C12H9ClO2S and a molecular weight of 252.72 g/mol. Its IUPAC name is 1-(benzenesulfonyl)-4-chlorobenzene.

What is 4-Chlorophenyl Phenyl Sulfone used for?

4-Chlorophenyl Phenyl Sulfone is supplied as a characterised reference material related to Dapsone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chlorophenyl Phenyl Sulfone can I order?

We supply 4-Chlorophenyl Phenyl Sulfone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chlorophenyl Phenyl Sulfone?

Yes. Every lot of 4-Chlorophenyl Phenyl Sulfone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chlorophenyl Phenyl Sulfone be shipped internationally?

Yes. 4-Chlorophenyl Phenyl Sulfone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.