Hydroxybenzotriazole Hydrate

About Hydroxybenzotriazole Hydrate

Hydroxybenzotriazole Hydrate is a metabolite or degradation product of Olaparib carrying the CAS registry number 80029-43-2. The compound has the formula C6H7N3O2, corresponding to a molecular weight of 153.14 g/mol. It is also known as 1-Hydroxybenzotriazole hydrate or 1-hydroxybenzotriazole monohydrate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Olaparib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Olaparib

View every impurity, metabolite and intermediate we list for Olaparib.

Olaparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxybenzotriazole Hydrate
Catalogue No.	VQ-032233
CAS Number	80029-43-2
IUPAC name	1-hydroxybenzotriazole;hydrate
Molecular formula	C₆H₇N₃O₂
Molecular weight	153.14 g/mol
Exact mass	153.0538
Grade	Reference Standard
HSN code	38229090
InChIKey	PJUPKRYGDFTMTM-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)N=NN2O.O
PubChem CID	2796029

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	51.9 Å²
Synonyms	1-Hydroxybenzotriazole hydrate, 1-hydroxybenzotriazole monohydrate, 1H-Benzotriazole, 1-hydroxy-, monohydrate, 1H-Benzotriazole, 1-hydroxy-, hydrate (1:1), 1-hydroxy-1H-benzotriazole monohydrate, 1H-Benzotriazole, 1-hydroxy-, hydrate, 1h-1,2,3-benzotriazol-1-ol hydrate, HOBt Hydrate, 1h-benzo[d][1,2,3]triazol-1-ol hydrate, 1-Hydroxybenzotriazolehydrate, N-Hydroxybenzotriazole hydrate

Safety & hazard information (GHS)

Explosive

Signal word: Danger

Hazard statements

H203(deleted) explosive, fire, blast or projection hazard

Precautionary statements: P210, P230, P240, P250, P280, P370 + P380, P372, P373, P401, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxybenzotriazole Hydrate?

The CAS Registry Number of Hydroxybenzotriazole Hydrate is 80029-43-2. It is also known as 1-Hydroxybenzotriazole hydrate, 1-hydroxybenzotriazole monohydrate, 1H-Benzotriazole, 1-hydroxy-, monohydrate.

What is the molecular formula and molecular weight of Hydroxybenzotriazole Hydrate?

Hydroxybenzotriazole Hydrate has the molecular formula C6H7N3O2 and a molecular weight of 153.14 g/mol.

What is Hydroxybenzotriazole Hydrate used for?

Hydroxybenzotriazole Hydrate is supplied as a characterised reference material related to Olaparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxybenzotriazole Hydrate can I order?

We supply Hydroxybenzotriazole Hydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxybenzotriazole Hydrate?

Yes. Every lot of Hydroxybenzotriazole Hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxybenzotriazole Hydrate be shipped internationally?

Yes. Hydroxybenzotriazole Hydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.